lncrna-regulatory-network-construction-analysis

lncrna-regulatory-network-construction-analysis is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 60 tokens per session (2,668 once invoked), scanned A, original, MIT.

A bioinformatics workflow that builds an lncRNA–mRNA network from local reference tables by linking them through shared microRNAs. lncRNAs are long non-coding RNA molecules, and microRNAs are small RNA molecules that can help regulate genes.

In plain words
What is it for?
Use it to connect candidate lncRNAs with target mRNAs, create evidence tables, save the analyzed network, and redraw its PDF visualization.
Why use it?
It provides a database-based lookup without pretending to infer regulation from gene-expression measurements. The resulting links can be traced through the shared microRNA evidence.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Needs its repository: it runs a file that does not travel with it, so clone the repository first. The line is --reference_dir ./references/database \.

Good fit Use it to connect candidate lncRNAs with target mRNAs, create evidence tables, save the analyzed network, and redraw its PDF visualization.

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About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

It runs from inside its repository, so the clone comes first — what it calls does not travel with the file alone.

Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills
agentmods
npx agentmods add skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for lncrna-regulatory-network-construction-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

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Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/lncrna-regulatory-network-construction-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 60 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,668 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00060 $0.02668
Opus 5 $0.00030 $0.01334
Sonnet 5 $0.00012 $0.00534
Haiku 4.5 $0.00006 $0.00267

Measured 12d ago against content hash bf7013ea1f74, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

lncrna-regulatory-network-construction-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Data Analysis/lncrna-regulatory-network-construction-analysis/SKILL.md · 267 lines

How it starts

The opening of the file, as written. The whole thing — 267 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

lncRNA Regulatory Network Construction Analysis

When to Use

Use this skill when the user wants a local-database network lookup workflow rather than expression-based inference.

Typical use cases:

  • Build an lncRNA-mRNA network from target genes and the bundled ceRNA reference tables
  • Start from a candidate lncRNA list and retrieve linked mRNAs through shared miRNAs
  • Generate an auditable lncRNA-mRNA network table plus a tripartite evidence table
  • Reuse a saved database-derived network object to regenerate a PDF plot

Do not use this skill when the user asks for:

  • Expression-matrix-based network inference
  • Correlation analysis between lncRNAs and mRNAs
  • Causal inference or regulatory-strength estimation from expression data
  • Online database querying or remote API lookups

Execution Model

This is a hybrid skill.

  1. Read SKILL.md to confirm that the request is database-driven.
  2. Use scripts/main.R for actual execution.
  3. Use --mode analyze to build tables and a saved .rda object.
  4. Use --mode visualize to reuse the saved object and redraw the PDF without rebuilding the database tables.
  5. Use --mode full to run both steps in one pass.
  6. Read reference files only when more detail is needed.
  7. Before --mode visualize, confirm that output_dir/data/lncrna_network.rda already exists.
  8. In visualize mode, the saved .rda object is the required input; a missing or invalid reference_dir does not block plot reuse.
  9. After execution, report the mode, output directory, key files, and either the retained network size or the surfaced skill error code.

When to Read External Files

Situation File to Read Purpose
Need algorithm details references/algorithm.md Understand the shared-miRNA projection logic
Need troubleshooting help references/troubleshooting.md Review error codes and fixes
Need CLI examples or the baseline record references/cli-guide.md Review installation, examples, and the recorded run
Need runnable demo inputs tests/data/ Use the bundled target gene and lncRNA lists
Need actual execution scripts/main.R Run the CLI workflow

Read the full file on GitHub · 267 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 267 lines · 60 tokens per session scan A bf7013ea1f74

Subscribe to this mod's changes

lncrna-regulatory-network-construction-analysis is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 60 tokens to every session and 2,668 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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