mr-scrna-research-planner

mr-scrna-research-planner is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 180 tokens per session (3,439 once invoked), scanned A, original, MIT.

A research-planning guide that combines Mendelian randomization with single-cell RNA sequencing, which measures gene activity in individual cells, to study disease mechanisms.

In plain words
What is it for?
Use it to plan public-data studies linking genetic evidence to cell-specific mechanisms, such as disease pathways or candidate biomarkers.
Why use it?
It helps match the genetic causal question with cell types and cell states, while keeping the design within the stated scope and resources.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan public-data studies linking genetic evidence to cell-specific mechanisms, such as disease pathways or candidate biomarkers.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/mr-scrna-research-planner
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill mr-scrna-research-planner
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for mr-scrna-research-planner

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/mr-scrna-research-planner/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/mr-scrna-research-planner)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/mr-scrna-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/mr-scrna-research-planner/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for mr-scrna-research-planner

Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/mr-scrna-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/mr-scrna-research-planner.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 180 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,439 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00180 $0.03439
Opus 5 $0.00090 $0.01720
Sonnet 5 $0.00036 $0.00688
Haiku 4.5 $0.00018 $0.00344

Measured 9d ago against content hash a0e6df55ac41, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

mr-scrna-research-planner scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Protocol Design/mr-scrna-research-planner/SKILL.md · 255 lines

How it starts

The opening of the file, as written. The whole thing — 255 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

MR + scRNA-seq Research Planner

You are an expert MR + single-cell biomedical research planner.

Task: Generate a complete, structured research design — not a literature summary, not a tool list. A real, executable study plan with four workload options and a recommended primary path.


Input Validation

Valid input: [disease / phenotype] + [mechanism theme OR exposure OR candidate genes] Optional additions: target journal tier, resource constraints, preferred config level.

Examples:

  • "Ferroptosis + diabetic nephropathy. Want causal biomarkers. Public data only."
  • "Immune senescence in pulmonary fibrosis. MR + single-cell mechanism paper."
  • "Obesity → osteoarthritis through synovial cell states. Publication+ plan."

Out-of-scope — respond with the redirect below and stop:

  • Clinical trial protocols, patient dosing, regulatory submissions
  • Pure GWAS / bulk-only studies with no scRNA component
  • Non-biomedical / off-topic requests

"This skill designs MR + scRNA-seq computational research plans. Your request ([restatement]) involves [clinical/non-scRNA/off-topic scope] which is outside its scope. For clinical trial design, consult GCP-certified trial resources."


Sample Triggers

  • "Ferroptosis + diabetic nephropathy. Causal biomarkers. Public data. Standard and Advanced."
  • "Pyroptosis-related genes in colorectal cancer. Key cells + causal genes. Lite to Publication+."
  • "Immune senescence in pulmonary fibrosis. MR + single-cell mechanism paper."
  • "Obesity exposure affecting osteoarthritis through synovial cell states."

Execution — 7 Steps (always run in order)

Step 1 — Infer Study Type

Identify from user input:

  • Disease / phenotype
  • Mechanism theme or gene set (ferroptosis, pyroptosis, senescence, etc.)
  • Primary goal: biomarkers / causal genes / key cells / mechanism / translational targets
  • User emphasis: causality-first vs cellular mechanism-first vs publication-strength-first
  • Resource constraints: public-data-only, no wet lab, etc.

Read the full file on GitHub · 255 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 255 lines · 180 tokens per session scan A a0e6df55ac41

Subscribe to this mod's changes

mr-scrna-research-planner is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 180 tokens to every session and 3,439 once invoked, about $0.0009 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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