non-tumor-mechanism-guided-diagnostic-ml-research-planner

non-tumor-mechanism-guided-diagnostic-ml-research-planner is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 135 tokens per session (3,758 once invoked), scanned A, original, MIT.

A study-planning guide for building non-cancer diagnostic machine-learning research from disease gene-expression data. It covers comparing diseased and control samples, selecting relevant genes, training models, and checking their diagnostic performance.

In plain words
What is it for?
Planning transcriptome-based diagnostic biomarker studies for diseases other than cancer. It can help define workflows involving differential-expression analysis, batch correction, machine-learning feature selection, ROC curves, calibration, and decision-curve analysis.
Why use it?
It turns a broad biomedical idea into a structured, executable study plan. This helps researchers decide how to prepare datasets, select features, validate models, and interpret biological results.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Planning transcriptome-based diagnostic biomarker studies for diseases other than cancer. It can help define workflows involving differential-expression analysis, batch correction, machine-learning feature selection, ROC curves, calibration, and decision-curve analysis.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/non-tumor-mechanism-guided-diagnostic-ml-research-planner
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,869 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill non-tumor-mechanism-guided-diagnostic-ml-research-planner
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for non-tumor-mechanism-guided-diagnostic-ml-research-planner

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/non-tumor-mechanism-guided-diagnostic-ml-research-planner/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/non-tumor-mechanism-guided-diagnostic-ml-research-planner)
Your own site
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Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

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Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/non-tumor-mechanism-guided-diagnostic-ml-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/non-tumor-mechanism-guided-diagnostic-ml-research-planner.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 135 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,758 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00135 $0.03758
Opus 5 $0.00068 $0.01879
Sonnet 5 $0.00027 $0.00752
Haiku 4.5 $0.00014 $0.00376

Measured 9d ago against content hash a46f18520d7b, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

non-tumor-mechanism-guided-diagnostic-ml-research-planner scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Protocol Design/non-tumor-mechanism-guided-diagnostic-ml-research-planner/SKILL.md · 255 lines

How it starts

The opening of the file, as written. The whole thing — 255 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

Non-Tumor Mechanism-Guided Diagnostic ML Research Planner

You are an expert conventional non-oncology biomarker and diagnostic-model research planner.

Task: Generate a complete, structured research design — not a literature summary, not a tool list. A real, executable study plan with four workload options and a recommended primary path.

This skill is designed for article patterns like: public disease-expression dataset selection → optional multi-dataset merging and batch correction → optional mechanism-related gene-family retrieval → DEG analysis → candidate-set restriction → feature-selection pipeline → diagnostic model construction → ROC / calibration / DCA evaluation → immune / regulatory interpretation → optional orthogonal validation. Do not mechanically copy any anchor paper; generalize the pattern into a reusable conventional non-oncology mechanism-guided diagnostic-ML study-design framework.

This skill must follow the same output discipline and standardization style as the conventional-non-oncology-hub-gene-research-planner baseline: explicit scope control, four mandatory workload configurations, one recommended primary plan, dependency-aware workflow logic, a mandatory reference literature pack, and a fixed self-critical risk review immediately after the literature section.


Input Validation

Valid input: [disease / condition] + [goal] + optional [mechanism-related gene family / pathway / biological theme] + [validation direction] Optional additions: public-data-only, GSEA interest, immune angle, TF/miRNA network interest, preferred config level, stricter feature-selection logic, batch-correction requirement, no wet lab.

Examples:

  • "Diabetic foot ulcer with pyroptosis-related genes, need diagnostic model and references."
  • "Chronic kidney disease plus oxidative stress theme, need ROC / calibration / DCA."
  • "Non-oncology inflammatory disease with mechanism-guided feature selection and immune context."
  • "Public multi-dataset diagnostic biomarker study with one external validation cohort."

Read the full file on GitHub · 255 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 255 lines · 135 tokens per session scan A a46f18520d7b

Subscribe to this mod's changes

non-tumor-mechanism-guided-diagnostic-ml-research-planner is a skill published in the GitHub repository aipoch/medical-research-skills (1,869 stars, last pushed today), licensed MIT. It adds 135 tokens to every session and 3,758 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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