Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.
Getting it into your agent
One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.
npx skills add aipoch/medical-research-skills --skill novelty-vs-feasibility-assessorgit clone --depth 1 https://github.com/aipoch/medical-research-skillsWrote this? Show the measurements
A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.
[](https://agentmods.dev/skills/aipoch/medical-research-skills/novelty-vs-feasibility-assessor)<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/novelty-vs-feasibility-assessor"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/novelty-vs-feasibility-assessor/github.svg" alt="Measured on agentmods" height="20"></a>Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/novelty-vs-feasibility-assessor"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/novelty-vs-feasibility-assessor.svg" alt="Reviewed on agentmods" width="80" height="20"></a>- NVIDIA SkillSpector pass
What it costs to keep this loaded
Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.
| Model | Per session | Once invoked |
|---|---|---|
| Fable 5.1 | $0.00074 | $0.02609 |
| Opus 5 | $0.00037 | $0.01305 |
| Sonnet 5 | $0.00015 | $0.00522 |
| Haiku 4.5 | $0.00007 | $0.00261 |
Grade A, and why
novelty-vs-feasibility-assessor scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.
A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.
Nothing flagged
None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.
How it starts
The opening of the file, as written. The whole thing — 302 lines — stays where its author put it; the contents beside it link to each section on GitHub.
Novelty vs Feasibility Assessor
You are an expert medical research topic-start decision analyst.
Task: Decide whether a proposed topic is worth starting now, under the user’s actual conditions — not whether it sounds interesting in theory, not whether it is merely “innovative,” and not whether it is simply technically possible.
This skill is for users who want to know:
- whether a topic is genuinely differentiated or only superficially novel,
- whether it is realistically executable with current data, samples, tools, collaborators, and timeline,
- what the narrowest publishable or decision-useful version would be,
- and whether the correct recommendation is to start, narrow, redesign, delay, or stop.
The output must balance novelty, feasibility, execution burden, validation burden, and likely project value. The goal is a start decision, not a vague evaluation.
Reference Module Integration
Use these files as execution standards:
-
references/novelty-audit-framework.md- Use for distinguishing true novelty from pseudo-novelty.
- Use when judging whether the proposed question, context, method, or integration is actually differentiated.
-
references/feasibility-burden-framework.md- Use for auditing data access, sample access, resource burden, method burden, validation burden, timeline burden, and dependency burden.
-
references/start-decision-bands.md- Use for the final start / narrow / redesign / stop recommendation.
- Use when converting the audit into an actionable launch decision.
-
references/minimal-executable-version-template.md- Use for constructing the minimum credible version of the project.
- Use whenever the original proposal is too broad, too expensive, too slow, or too dependency-heavy.
-
references/literature-and-resource-integrity-rules.md- Use before naming precedent studies, dataset availability, assay access, platform access, or publication potential.
- Use for all reference and resource-status claims.
What ships with it
15 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.
- eval_report_novelty-vs-feasibility-assessor_result.json 24 KB
- references/decision-band-rules.md 333 B
- references/feasibility-burden-framework.md 517 B
- references/feasibility-dimension-checklist.md 405 B
- references/literature-and-resource-integrity-rules.md 672 B
- references/literature-integrity-rules.md 376 B
- references/minimal-executable-version-template.md 544 B
- references/novelty-assessment-framework.md 729 B
- references/novelty-audit-framework.md 932 B
- references/output-section-guidance.md 259 B
- references/pseudo-novelty-rejection-rules.md 319 B
- references/publication-potential-and-value-rules.md 444 B
- references/resource-and-dependency-burden-rules.md 438 B
- references/start-decision-bands.md 766 B
- references/workflow-step-template.md 269 B
What this file has done since we first saw it
Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.
- 9d ago First seen · 302 lines · 74 tokens per session scan A 203ee362cecf
novelty-vs-feasibility-assessor is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 74 tokens to every session and 2,609 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.
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chromatin-regulation
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spatial-omics
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atac-seq-bam-read-alignment-processing
Use when when you have aligned ATAC-seq BAM files and need to quantify Tn5 transposase insertion patterns around specific genomic coordinates (motif sites, peaks, regulatory regions) to detect transcription factor occupancy footprints or compare chromatin accessibility between bound and unbound.
bedgraph-file-format-manipulation
Use when you have aligned ChIP-Seq reads (in BED or BEDPE format) and need to convert them into quantitative genome-wide signal tracks (coverage, p-value, or q-value scores) for downstream statistical comparison or peak detection.