Getting it into your agent
One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.
npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-depmapgit clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-SkillsWrote this? Show the measurements
A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.
[](https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-depmap)<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-depmap"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-depmap/github.svg" alt="Measured on agentmods" height="20"></a>Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-depmap"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-depmap.svg" alt="Reviewed on agentmods" width="80" height="20"></a>- NVIDIA SkillSpector warn
SkillSpector: 2 findings, up to medium
These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →
- medium Data Exfiltration · line 25 Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
- medium Data Exfiltration · line 72 Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
What it costs to keep this loaded
Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.
| Model | Per session | Once invoked |
|---|---|---|
| Fable 5.1 | $0.00077 | $0.03520 |
| Opus 5.5 | $0.00031 | $0.01408 |
| Sonnet 5.5 | $0.00015 | $0.00704 |
| Haiku 4.5 | $0.00008 | $0.00352 |
Grade A, and why
alterlab-depmap scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 1mo ago.
A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.
Makes network callslowCapability
Not a fault in itself. Listed so you know the mod talks to something, and to what.
allowed-tools: Read WebFetch Bash(curl:*) Bash(python:*) How it starts
The opening of the file, as written. The whole thing — 311 lines — stays where its author put it; the contents beside it link to each section on GitHub.
DepMap — Cancer Dependency Map
Overview
The Cancer Dependency Map (DepMap) project, run by the Broad Institute, systematically characterizes genetic dependencies across hundreds of cancer cell lines using genome-wide CRISPR knockout screens (DepMap CRISPR), RNA interference (RNAi), and compound sensitivity assays (PRISM). DepMap data is essential for:
- Identifying which genes are essential for specific cancer types
- Finding cancer-selective dependencies (therapeutic targets)
- Validating oncology drug targets
- Discovering synthetic lethal interactions
Key resources:
- DepMap Portal: https://depmap.org/portal/
- DepMap data downloads: https://depmap.org/portal/data_page/
- Figshare deposits (programmatic, keyless): https://api.figshare.com/v2/articles/{article_id}
Access model — read this first. DepMap has no documented, stable public REST API for gene-level queries, and the portal (including depmap.org/portal/api/... and the data page) now sits behind a Cloudflare browser-verification check that asks users not to scrape it — scripted requests get the verification page, not data. The supported workflow is: download the release matrix CSVs, then analyse them locally with pandas. The keyless programmatic path to those files is the Figshare API for releases up to 24Q4 (/articles/{id}/files?page_size=1000 lists name + download_url; the endpoint is paginated, 10 files per page by default); scripts/query_depmap.py wraps this. Newer releases (25Q2 onward; latest 26Q1, April 2026) are downloaded in a browser from the data page. For Sanger's Project Score CRISPR screens there is a keyless JSON:API at https://api.cellmodelpassports.sanger.ac.uk (non-commercial use).
When to Use This Skill
Use DepMap when:
- Target validation: Is a gene essential for survival in cancer cell lines with a specific mutation (e.g., KRAS-mutant)?
- Biomarker discovery: What genomic features predict sensitivity to knockout of a gene?
- Synthetic lethality: Find genes that are selectively essential when another gene is mutated/deleted
- Drug sensitivity: What cell line features predict response to a compound?
- Pan-cancer essentiality: Is a gene broadly essential across all cancer types (bad target) or selectively essential?
- Correlation analysis: Which pairs of genes have correlated dependency profiles (co-essentiality)?
What ships with it
3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.
What this file has done since we first saw it
Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.
- 1mo ago Changed · +25 lines 8f9dd62c2182
- 1mo ago First seen · 286 lines · 77 tokens per session scan A b03e764f27d2
alterlab-depmap is a skill published in the GitHub repository AlterLab-IEU/AlterLab-Academic-Skills (78 stars, last pushed 2d ago), licensed MIT. It adds 77 tokens to every session and 3,520 once invoked, about $0.0003 per session on Opus 5.5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.
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