alterlab-geniml

alterlab-geniml is a skill for Claude Code from AlterLab-IEU/AlterLab-Academic-Skills. It costs 152 tokens per session (3,178 once invoked), scanned A, original, MIT.

A Python toolkit for machine learning on genomic interval data, which records regions of DNA in BED files. It can turn genomic regions, metadata, and single-cell ATAC-seq data into numerical representations for comparison and analysis.

In plain words
What is it for?
Use it to find similar genomic regions, cluster regions or cells, combine regions with metadata, create consensus peak sets, and prepare BED data for machine learning.
Why use it?
It removes the need to build common genomic-region processing and embedding workflows from scratch. It also provides ways to create shared peak regions and randomized BED data for analysis.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Part of the alterlab-domain-specific plugin — 18 skills shipped together

Good fit Use it to find similar genomic regions, cluster regions or cells, combine regions with metadata, create consensus peak sets, and prepare BED data for machine learning.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-geniml
Clone the repo
git clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-Skills

Made for: Claude Code.

Or install alterlab-domain-specific, the plugin that ships this one along with the rest of its 18 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for alterlab-geniml

README.md
[![agentmods](https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml/github.svg)](https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml)
Your own site
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for alterlab-geniml

Your own site · 80×15
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-geniml.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 152 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,178 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high YARA Match · line 28
    YARA rule matched a known malware signature (reverse shell, backdoor, ransomware, C2 framework, or info stealer).
    Fix: Remove the malware payload or compromised file entirely. Investigate how it entered the skill and audit all other artifacts for additional indicators of compromise.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00152 $0.03178
Opus 5 $0.00076 $0.01589
Sonnet 5 $0.00030 $0.00636
Haiku 4.5 $0.00015 $0.00318

Measured 6d ago against content hash 6f4e0f877186, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

alterlab-geniml scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/domain-specific/alterlab-geniml/SKILL.md · 299 lines

How it starts

The opening of the file, as written. The whole thing — 299 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Geniml: Genomic Interval Machine Learning

Overview

Geniml is a Python package for building machine learning models on genomic interval data from BED files. It provides unsupervised methods for learning embeddings of genomic regions, single cells, and metadata labels, enabling similarity searches, clustering, and downstream ML tasks.

Installation

Verified against geniml 0.8.4. Install with uv (prefer uv run --with for one-off runs so nothing leaks into the project env):

uv pip install 'geniml[ml]'        # [ml] pulls torch/gensim; needed for region2vec/scembed

scEmbed and scATAC-seq examples also need scanpy: uv pip install scanpy. Universe building (build-universe) and hard tokenization shell out to external binaries — uniwig (coverage tracks) and bedtools — so install those separately.

Development version: uv pip install git+https://github.com/databio/geniml.git

Import paths (IMPORTANT — verified gotcha)

geniml's subpackage __init__.py files do not re-export their internals, so the obvious short imports fail with ImportError. Import from the concrete module instead:

Want Wrong (fails) Correct (verified)
Hard tokenization from geniml.tokenization import hard_tokenization from geniml.tokenization.main import hard_tokenization_main
Region2Vec (legacy fn) from geniml.region2vec import region2vec from geniml.region2vec.main_legacy import region2vec
Region2Vec (model class) from geniml.region2vec.main import Region2VecExModel
scEmbed from geniml.scembed import ScEmbed from geniml.scembed.main import ScEmbed
Token dataset from geniml.io import tokenize_cells (does not exist) from geniml.region2vec.utils import Region2VecDataset
Tokenizer from gtars.tokenizers import Tokenizer

Tokenizing cells is handled internally by ScEmbed via a gtars Tokenizer; there is no geniml.io.tokenize_cells function.

Read the full file on GitHub · 299 lines

Files

What ships with it

6 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 299 lines · 152 tokens per session scan A 6f4e0f877186

Subscribe to this mod's changes

alterlab-geniml is a skill published in the GitHub repository AlterLab-IEU/AlterLab-Academic-Skills (66 stars, last pushed 7d ago), licensed MIT. It adds 152 tokens to every session and 3,178 once invoked, about $0.0008 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-05.

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