trajectory-analysis

trajectory-analysis is a skill for Claude Code, Codex from awslabs/hcls-agent-skills. It costs 141 tokens per session (4,165 once invoked), scanned A, original, MIT-0.

A single-cell biology analysis guide for finding likely cell-development paths from individual-cell data. It covers pseudotime, which orders cells along a possible process, RNA velocity, cell-state transitions, and likely final cell states.

In plain words
What is it for?
Inferring cell trajectories, studying differentiation, estimating RNA velocity, mapping cell fates, identifying branches with PAGA, and finding terminal states with CellRank.
Why use it?
It helps researchers study how cells may change, differentiate, or branch into different lineages. It brings several trajectory-analysis methods into one pipeline.

Skill for Claude CodeCodex ✓ vendor

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

Good fit Inferring cell trajectories, studying differentiation, estimating RNA velocity, mapping cell fates, identifying branches with PAGA, and finding terminal states with CellRank.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/awslabs/hcls-agent-skills/trajectory-analysis
About the project

awslabs/hcls-agent-skills is a collection of reusable instructions that help AI agents handle healthcare and life sciences work, including genomics, medical imaging, claims, and drug discovery. It is intended for agents running on Agent Skills-compatible platforms, and the catalogue entries are its individual domain skills.

awslabs/hcls-agent-skills · 31 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add awslabs/hcls-agent-skills --skill trajectory-analysis
Clone the repo
git clone --depth 1 https://github.com/awslabs/hcls-agent-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for trajectory-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/awslabs/hcls-agent-skills/trajectory-analysis/github.svg)](https://agentmods.dev/skills/awslabs/hcls-agent-skills/trajectory-analysis)
Your own site
<a href="https://agentmods.dev/skills/awslabs/hcls-agent-skills/trajectory-analysis"><img src="https://agentmods.dev/badge/skills/awslabs/hcls-agent-skills/trajectory-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for trajectory-analysis

Your own site · 80×15
<a href="https://agentmods.dev/skills/awslabs/hcls-agent-skills/trajectory-analysis"><img src="https://agentmods.dev/badge/skills/awslabs/hcls-agent-skills/trajectory-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 141 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,165 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00141 $0.04165
Opus 5 $0.00071 $0.02083
Sonnet 5 $0.00028 $0.00833
Haiku 4.5 $0.00014 $0.00417

Measured 10d ago against content hash cb96748f40db, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

trajectory-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/trajectory-analysis/SKILL.md · 352 lines

The source is not reproduced here

Licensed MIT-0

The repository is licensed MIT-0, which this catalogue does not treat as permission to reproduce the file. Read it at the source.

Read it on GitHub

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 352 lines · 141 tokens per session scan A cb96748f40db

Subscribe to this mod's changes

trajectory-analysis is a skill published in the GitHub repository awslabs/hcls-agent-skills (31 stars, last pushed 9d ago), licensed MIT-0. It adds 141 tokens to every session and 4,165 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

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aristoteleo/PantheonOS · 129 tokens

bulkrna-trajblend

Load when placing bulk RNA-seq samples on a single-cell reference's pseudotime axis (NNLS deconvolution + nearest-neighbour mapping). Skip when plain cell-type proportions (use bulkrna-deconvolution); native single-cell trajectory inference (use sc-pseudotime).

TianGzlab/OmicsClaw · 65 tokens

sc-consensus-pseudotime

Load when you want a single-cell pseudotime ordering robust to the choice of trajectory method — fanning out DPT/Palantir/VIA from a shared root, rank-aligning them, and voting a consensus pseudotime with per-cell uncertainty. Skip when you have branching multi-lineage trajectories; no defined root.

TianGzlab/OmicsClaw · 74 tokens

Single-Cell Analysis Skills Index

Core skills for single-cell RNA-seq analysis: quality control, cell type annotation, and trajectory inference. These are high-priority actionable workflows — load them first for common single-cell tasks.

aristoteleo/PantheonOS · 48 tokens

sc-pseudotime

Load when ordering cells along a developmental trajectory in a normalised scRNA AnnData via DPT, Palantir, VIA, CellRank, Slingshot (R), or Monocle3 (R). Skip when ranking marker genes per cluster (use sc-markers); RNA velocity vector fields (use sc-velocity).

TianGzlab/OmicsClaw · 72 tokens

spatial-trajectory

Load when inferring pseudotime / lineage trajectories on a preprocessed spatial AnnData via DPT (default — diffusion pseudotime), CellRank (terminal-state + fate-probability), or Palantir (waypoint branch probabilities). Skip when the data has spliced/unspliced layers and you want velocity-driven dynamics (use…

TianGzlab/OmicsClaw · 93 tokens