Autonomous coding agent. Delegate any task that involves understanding, writing, or running code — from a GitHub issue, a bug report, or a user request. It explores, implements, and verifies on its own.
Deploy, diff, or destroy the ABCA CDK stack. Handles pre-deployment validation, synthesis, and post-deployment verification. Use when the user says "deploy", "cdk deploy", "deploy the stack", "destroy", "cdk diff", "what changed", "redeploy", or "update the stack".
Onboard a new GitHub repository to the ABCA platform so the agent can target it. Use when the user says "onboard a repo", "add a repository", "register a repo", "new repo", or gets a REPONOTONBOARDED / 422 error about an unregistered repository.
Evaluates AWS Health event impact on application workloads using topology knowledge. Determines blast radius, affected teams, and notification routing. Use this skill when investigating incidents triggered by AWS Health events including scheduled maintenance, operational issues, and service degradation notifications.
Create and update AgentCore runtime agents in a DEPLOYED instance of this accelerator. Use whenever the user wants to create a new agent, build an orchestrator/swarm/graph agent, add or remove tools/MCP-servers/skills from an existing agent, change an agent's model or system prompt, or otherwise modify a live runtime…
Propose a Terraform mirror plan for the most recent CDK commit on this branch. Use whenever the user has just committed CDK changes and says things like "mirror this to terraform", "propose tf changes", "what's the terraform equivalent", "tf follow-up", "sync to terraform", or any variation that signals they want the…
Prepare a development branch for a pull request to main. Run /code-review and ASH security scan, auto-fix high-confidence issues, then draft a PR title and body. Use this whenever the user signals intent to open a PR ("create a PR", "open a PR", "ready to PR", "submit PR", "PR this branch", "let's PR this"), even if…
Reason about drug repurposing strategies in HCLS — choosing between target-based and phenotype-based approaches, evaluating mechanism-of-action overlap, querying drug-gene interaction databases, assessing clinical translatability, and ranking candidates by evidence strength. Use when the user asks to repurpose a drug…
Reason about germline and somatic variant classification using ACMG/AMP 2015 and AMP/ASCO/CAP frameworks. Use when the user asks to classify a variant, interpret a VCF annotation, resolve a VUS, apply ACMG criteria, weigh ClinVar evidence, evaluate gnomAD allele frequencies, interpret REVEL/CADD/SpliceAI scores…
Reason about SaMD (Software as a Medical Device) regulatory compliance for FDA, EU MDR, and global submissions. Use when the user asks about IEC 62304 safety classification, ISO 14971 risk management, 21 CFR 820/QMSR quality system requirements, Design History File structure, 510(k)/De Novo/PMA pathway selection…