biosymphony-structure-factory

biosymphony-structure-factory is a skill for Claude Code, Codex from BioSymphony/structure-factory. It costs 43 tokens per session (1,875 once invoked), scanned A, original, MIT.

A planning tool for structural biology work, such as studying the shapes of biological molecules and designing candidate binders. It turns a research idea into a multi-step campaign that other workers can continue and check.

In plain words
What is it for?
Use it to plan target studies, compare models, rank candidates, map structures, define cloud-GPU work, and prepare task packs for systems such as Symphony or Linear.
Why use it?
It organizes long-running biology projects that would be difficult to manage as a single request or answer.

Skill for Claude CodeCodex

Written for Claude Code and Codex: shipped in a Claude Code plugin, but also agents/openai.yaml present. Also seen: mentions AGENTS.md.

Part of the biosymphony-structure-factory plugin — 2 skills shipped together , and of biosymphony-structure-factory

Good fit Use it to plan target studies, compare models, rank candidates, map structures, define cloud-GPU work, and prepare task packs for systems such as Symphony or Linear.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/biosymphony/structure-factory/biosymphony-structure-factory
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add BioSymphony/structure-factory --skill biosymphony-structure-factory
Clone the repo
git clone --depth 1 https://github.com/BioSymphony/structure-factory

Made for: Claude Code, Codex.

Or install biosymphony-structure-factory, the plugin that ships this one along with the rest of its 2 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for biosymphony-structure-factory

README.md
[![agentmods](https://agentmods.dev/badge/skills/biosymphony/structure-factory/biosymphony-structure-factory/github.svg)](https://agentmods.dev/skills/biosymphony/structure-factory/biosymphony-structure-factory)
Your own site
<a href="https://agentmods.dev/skills/biosymphony/structure-factory/biosymphony-structure-factory"><img src="https://agentmods.dev/badge/skills/biosymphony/structure-factory/biosymphony-structure-factory/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for biosymphony-structure-factory

Your own site · 80×15
<a href="https://agentmods.dev/skills/biosymphony/structure-factory/biosymphony-structure-factory"><img src="https://agentmods.dev/badge/skills/biosymphony/structure-factory/biosymphony-structure-factory.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 43 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,875 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00043 $0.01875
Opus 5.5 $0.00017 $0.00750
Sonnet 5.5 $0.00009 $0.00375
Haiku 4.5 $0.00004 $0.00187

Measured 19d ago against content hash 2859f835fd74, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

biosymphony-structure-factory scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 19d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/biosymphony-structure-factory/SKILL.md · 140 lines

How it starts

The opening of the file, as written. The whole thing — 140 lines — stays where its author put it; the contents beside it link to each section on GitHub.

BioSymphony Structure Factory

Use the tool knowledge base to select methods for a target, accession, or screening request. Call configured tools through the CLI or installed platform skills, connect stage outputs, and compare structures and candidate rankings.

Start with the requested outcome

Read references/README.md, references/AGENTS.md, and references/NON_CLAIMS.md, then select the work:

Request Deliverable
Choose tools Methods, input/output requirements, source references, and runtime options
Call and chain tools Configured adapters, stage dependencies, and checked downstream inputs
Plan a campaign Target definition, selected tools, and stage contracts
Demonstrate a workflow Public or synthetic inputs with a labeled example report
Prepare GPU execution Provider profile, resource limits, launch request, and validation commands
Review results Candidate ranking or structure report with source files and validation results
Run a campaign Authorized execution followed by artifact verification and resource cleanup

For ambiguous inputs, tools, or spending limits, use references/docs/intake-interview.md to resolve the missing decisions. For a first campaign, use references/docs/quickstart-tour.md; find command options in references/docs/cli-reference.md.

Bundled references keep links to included files local. Links to repository files outside this compact bundle point to the canonical public GitHub tree. Use the selected repository checkout for CLI commands and runtime files.

Read the references for your task

Task References
Find methods Full tool index, software registry, references/docs/tool-and-skill-radar.md
Select tools and compute references/docs/tooling-and-licensing.md, references/docs/compute-backends.md
Plan binder comparisons references/docs/binder-lane-round.md, references/docs/binder-study-decision-loop.md
Choose measured controls references/docs/binder-controls.md
Qualify candidate filters Binder filtering, filter qualification contract
Compare pH contributions pH comparison, ProtonPottsMPNN
Review design inputs GuideFlip measurements, glycan context
Select property-aligned sequence design MoMPNN
Compare protein-ligand scores Affinity scoring card: input modality, endpoint, scale, and pose controls
Plan Slurm prediction phases BioNeMo pipeline card: MSA handoffs, backend policy, and phase receipts
Use BindCraft2 references/tools/bindcraft2.md: presets, resource limits, output tables, score scales, and license
Qualify Anthropic acceleration references/tools/anthropic-optimization-kits.md: stock revision, runtime isolation, activation, and matched comparisons
Score or render predictions references/docs/confidence-sidecars.md
Prepare provider execution references/docs/preflight-checklist.md, references/docs/operational-gotchas.md; add references/docs/runpod-stack.md for RunPod
Coordinate workers references/docs/agentic-biology-harness.md, references/docs/linear-orchestration.md
Define run completion checks references/docs/no-false-success-hardening.md, references/docs/agent-run-learnings.md
Verify prediction artifacts Prediction handoff contract

Read the full file on GitHub · 140 lines

Files

What ships with it

60 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 19d ago Changed · +3 lines 2859f835fd74
  2. 25d ago Changed · +7 lines e730d86e1bca
  3. 1mo ago Changed · +9 lines · -2 tokens per session 7a77aab370cb
  4. 1mo ago Changed · +8 lines · -2 tokens per session 92e6cfa84c19
  5. 1mo ago Changed · +1 lines 87a9e95be95d
  6. 1mo ago First seen · 112 lines · 47 tokens per session scan A 3f6d5b993906

Subscribe to this mod's changes

biosymphony-structure-factory is a skill published in the GitHub repository BioSymphony/structure-factory (13 stars, last pushed 14d ago), licensed MIT. It adds 43 tokens to every session and 1,875 once invoked, about $0.0002 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.