deeptools

deeptools is a skill for Claude Code from K-Dense-AI/scientific-agent-skills. It costs 51 tokens per session (4,326 once invoked), scanned A, original, MIT.

A set of command-line tools for analysing high-throughput DNA sequencing data. It works with experiments such as ChIP-seq, RNA-seq and ATAC-seq to check data quality, compare samples and create genomic plots.

In plain words
What is it for?
Converting BAM alignment files into normalised coverage tracks, checking sequencing quality, comparing treatment and control samples, and making heatmaps or profile plots around features such as transcription start sites and peaks.
Why use it?
It removes the need to assemble separate tools for coverage conversion, quality checks and visualisation. It helps reveal poor-quality samples, differences between samples and where signals occur in the genome.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Good fit Converting BAM alignment files into normalised coverage tracks, checking sequencing quality, comparing treatment and control samples, and making heatmaps or profile plots around features such as transcription start sites and peaks.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/k-dense-ai/scientific-agent-skills/deeptools
About the project

Scientific Agent Skills is a collection of reusable procedures that give AI agents capabilities for scientific research across areas such as biology, chemistry, medicine, and drug discovery. It is used by researchers and by people building AI scientist workflows with compatible coding agents. The catalogue contains many of the project's skills and supporting instructions.

K-Dense-AI/scientific-agent-skills · 54,587 stars · on GitHub · arxiv.org

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add K-Dense-AI/scientific-agent-skills --skill deeptools
Clone the repo
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for deeptools

README.md
[![agentmods](https://agentmods.dev/badge/skills/k-dense-ai/scientific-agent-skills/deeptools/github.svg)](https://agentmods.dev/skills/k-dense-ai/scientific-agent-skills/deeptools)
Your own site
<a href="https://agentmods.dev/skills/k-dense-ai/scientific-agent-skills/deeptools"><img src="https://agentmods.dev/badge/skills/k-dense-ai/scientific-agent-skills/deeptools/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for deeptools

Your own site · 80×15
<a href="https://agentmods.dev/skills/k-dense-ai/scientific-agent-skills/deeptools"><img src="https://agentmods.dev/badge/skills/k-dense-ai/scientific-agent-skills/deeptools.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 51 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,326 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • Socket pass 2 Oct 2026
  • Snyk pass 2 Oct 2026
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00051 $0.04326
Opus 5.5 $0.00020 $0.01730
Sonnet 5.5 $0.00010 $0.00865
Haiku 4.5 $0.00005 $0.00433

Measured 24d ago against content hash f09f32bad2d0, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

deeptools scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 24d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (scripts/validate_files.py, scripts/workflow_generator.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

Copies of this mod

8 near-identical copies found in the catalogue:

  • deeptools — 100% identical, 97 lines differ
  • deeptools — 89% identical, 80 lines differ
  • deeptools — 84% identical, 235 lines differ
  • deeptools — 84% identical, 235 lines differ
  • deeptools — 84% identical, 235 lines differ
  • deeptools — 81% identical, 247 lines differ
  • deeptools — 78% identical, 244 lines differ
  • deeptools — 78% identical, 240 lines differ
skills/deeptools/SKILL.md · 436 lines

How it starts

The opening of the file, as written. The whole thing — 436 lines — stays where its author put it; the contents beside it link to each section on GitHub.

deepTools: NGS Data Analysis Toolkit

Overview

deepTools is a comprehensive suite of Python command-line tools designed for processing and analyzing high-throughput sequencing data. Use deepTools to perform quality control, normalize data, compare samples, and generate publication-quality visualizations for ChIP-seq, RNA-seq, ATAC-seq, MNase-seq, and other NGS experiments.

Core capabilities:

  • Convert BAM alignments to normalized coverage tracks (bigWig/bedGraph)
  • Quality control assessment (fingerprint, correlation, coverage)
  • Sample comparison and correlation analysis
  • Heatmap and profile plot generation around genomic features
  • Enrichment analysis and peak region visualization

When to Use This Skill

This skill should be used when:

  • File conversion: "Convert BAM to bigWig", "generate coverage tracks", "normalize ChIP-seq data"
  • Quality control: "check ChIP quality", "compare replicates", "assess sequencing depth", "QC analysis"
  • Visualization: "create heatmap around TSS", "plot ChIP signal", "visualize enrichment", "generate profile plot"
  • Sample comparison: "compare treatment vs control", "correlate samples", "PCA analysis"
  • Analysis workflows: "analyze ChIP-seq data", "RNA-seq coverage", "ATAC-seq analysis", "complete workflow"
  • Working with specific file types: BAM files, bigWig files, BED region files in genomics context

Quick Start

For users new to deepTools, start with file validation and common workflows:

1. Validate Input Files

Before running any analysis, validate BAM, bigWig, and BED files using the validation script:

python scripts/validate_files.py --bam sample1.bam sample2.bam --bed regions.bed

This checks local files, readable BAM/BAI/CSI structure and coordinate order, bigWig headers, and every BED row. It does not establish assembly identity or biological suitability.

2. Generate Workflow Template

For standard analyses, use the workflow generator to create customized scripts:

Read the full file on GitHub · 436 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 24d ago Changed · +6 lines f09f32bad2d0
  2. 25d ago Changed b365805c4b42
  3. 1mo ago Changed · +17 lines b8f6a7f39c5e
  4. 1mo ago First seen · 413 lines · 51 tokens per session scan A 2724906bdf23

Subscribe to this mod's changes

deeptools is a skill published in the GitHub repository K-Dense-AI/scientific-agent-skills (54,587 stars, last pushed 7d ago), licensed MIT. It adds 51 tokens to every session and 4,326 once invoked, about $0.0002 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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