proteomics-structural

proteomics-structural is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 88 tokens per session (1,048 once invoked), scanned A, original, Apache-2.0.

A tool for summarising cross-linking mass-spectrometry results, where chemical links reveal relationships between parts of proteins. It separates links within one protein from links between proteins and can check them against distance limits for common cross-linkers.

In plain words
What is it for?
Use it to filter and classify cross-links and produce structural-summary tables.
Why use it?
It helps assess whether detected links meet expected structural distance constraints after the data has already been searched.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to filter and classify cross-links and produce structural-summary tables.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/proteomics-structural
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill proteomics-structural
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for proteomics-structural

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/proteomics-structural/github.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/proteomics-structural)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/proteomics-structural"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/proteomics-structural/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for proteomics-structural

Your own site · 80×15
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/proteomics-structural"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/proteomics-structural.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 88 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,048 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 2 findings, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
  • medium analysis-evasion · line 1
    Suspicious Unicode normalization or mixed-script content
    Fix: Review the flagged content for security risks. Ensure no credentials, secrets, or sensitive data are exposed.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00088 $0.01048
Opus 5.5 $0.00035 $0.00419
Sonnet 5.5 $0.00018 $0.00210
Haiku 4.5 $0.00009 $0.00105

Measured 20d ago against content hash 4fadcd86402c, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

proteomics-structural scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 20d ago.

The scan reads SKILL.md. This mod also ships 5 executable files (_api.py, examples/example_step.py, struct_proteomics.py, …), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/proteomics/proteomics-structural/SKILL.md · 125 lines

How it starts

The opening of the file, as written. The whole thing — 125 lines — stays where its author put it; the contents beside it link to each section on GitHub.

proteomics-structural

When to use

The CLI defaults are DSS and fdr_threshold=0.05. DSS/BS3/DSSO/DSBU use 30 angstrom; EDC uses 20 angstrom. Use existing search-engine tables; this skill does not search raw spectra.

Use from a step

from skills._sdk.notebook import load_skill, write_output
library = load_skill('proteomics-structural')
data = library.demo_data(random_state=42)
result = library.analyse_crosslinks(data)
write_output(result, 'tables/crosslinks.csv')

For real data, use read_input and pass any read_table helper as reader=. The executable examples/example_step.py also checks the result and writes a Figure.

API

analyse_crosslinks(data: pd.DataFrame, *, fdr_threshold: float=0.05, crosslinker: str='DSS') -> pd.DataFrame

Return filtered crosslinks with protein-pair and optional distance classifications.

:param data: Crosslink rows with protein_a and protein_b, optional fdr and distance_angstrom. :param fdr_threshold: CLI default 0.05; filters only when an fdr column is present. :param crosslinker: CLI default DSS; BS3, DSSO and DSBU use 30 A, EDC uses 20 A. :returns: New crosslink table; absent distance evidence remains unchecked in run_info. :raises ValueError: Protein identifiers, crosslinker or confidence threshold are invalid.

run_info(table: pd.DataFrame, *, keep: bool=True) -> dict

Read crosslink analysis diagnostics.

:param table: Output of analyse_crosslinks. :param keep: True preserves attrs; False removes diagnostics. :returns: A separate dictionary stating which optional checks ran. :raises TypeError: The input is not a DataFrame.

distance_figure(table: pd.DataFrame)

Plot measured crosslink distances.

:param table: Crosslinks containing distance_angstrom. :returns: A matplotlib Figure without writing files. :raises KeyError: distance_angstrom is absent.

demo_data(*, random_state: int=42) -> pd.DataFrame

Read the full file on GitHub · 125 lines

Files

What ships with it

8 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 20d ago Changed · +19 lines 4fadcd86402c
  2. 1mo ago First seen · 106 lines · 88 tokens per session scan A f5a3d131dfc8

Subscribe to this mod's changes

proteomics-structural is a skill published in the GitHub repository TianGzlab/OmicsClaw (161 stars, last pushed 20d ago), licensed Apache-2.0. It adds 88 tokens to every session and 1,048 once invoked, about $0.0004 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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