TianGzlab/OmicsClaw

Conversational & memory-enabled AI research partner for multi-omics analysis. CLI + Desktop App (installers in Releases). From biological idea to full research paper.

159Stars on the repository
60Mods indexed here, across every type
1mo agoLast push, which is what freshness is scored on
Apache-2.0Licence, which decides whether bodies are shown

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Systematic workflow for clustering biological samples, features, or any quantitative data matrix. Implements multiple clustering algorithms with rigorous validation, comparison, and interpretation to identify meaningful data groupings.

159 1mo ago A 6 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Skill "Cell-Cell Communication Analysis (CellChat)" from TianGzlab/OmicsClaw, covering cell-cell communication analysis (cellchat v2), when to use this skill, installation, inputs and outputs.

159 1mo ago A 9 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Compare two groups of experiments to identify differential peak regions (DPR) or differentially methylated regions (DMR) using the ChIP-Atlas Diff Analysis API.

159 1mo ago A 6 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Find ChIP-seq peak enrichment near your genes using the official ChIP-Atlas Enrichment Analysis API.

159 1mo ago A 7 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Find target genes for any transcription factor using pre-computed ChIP-Atlas public ChIP-seq data.

159 1mo ago A 6 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Skill "ClinicalTrials.gov Disease Landscape Scanner" from TianGzlab/OmicsClaw, covering clinicaltrials.gov disease landscape scanner, when to use this skill, installation, inputs and outputs.

159 1mo ago A 6 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Build weighted gene co-expression networks to identify modules of coordinately expressed genes and discover hub genes that may be key regulators. This workflow uses WGCNA (Weighted Gene Co-expression Network Analysis) to group genes into modules based on their expression patterns across samples, then correlates these…

159 1mo ago A 11 tokens original Apache-2.0

Experimental Design

10

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Comprehensive workflow for statistical experimental design in genomics, from power analysis and sample size determination to batch-balanced experimental layouts and multiple testing strategy.

159 1mo ago A 2 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Annotate genomic variants in VCF files with functional effects, clinical significance, and pathogenicity predictions.

159 1mo ago A 4 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Infer gene regulatory networks (GRNs) de novo from single-cell RNA-seq data using pySCENIC. This workflow discovers transcription factor (TF) regulons directly from expression patterns and calculates cell-level TF activity scores.

159 1mo ago A 11 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Identify genes whose genetically regulated expression is associated with disease risk, determine therapeutic directionality (inhibit vs. activate), and prioritize drug targets with causal genetic evidence using Transcriptome-Wide Association Study (TWAS) analysis.

159 1mo ago A 7 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Select minimal, interpretable biomarker panels from high-dimensional omics data using penalized logistic regression (LASSO/elastic net) with nested cross-validation and stability selection.

159 1mo ago A 9 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Search Consensus (consensus.app) for preclinical studies on a molecular target in a disease, then extract structured in vitro and in vivo experiment details from each paper.

159 1mo ago A 4 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Identify latent factors driving variation across 2+ omics layers using MOFA+ (Multi-Omics Factor Analysis). Decomposes multi-omics data into interpretable factors, each capturing shared or view-specific biological signal. Handles missing data across views natively.

159 1mo ago A 9 tokens original Apache-2.0

PCR Primer Design

19

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Comprehensive PCR and qPCR primer design following MIQE 2.0 guidelines with automated validation.

159 1mo ago C 3 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Analyze pooled CRISPR screens with single-cell RNA-seq readout using a tiered workflow: fast screening → target validation → rigorous differential expression.

159 1mo ago A 7 tokens original Apache-2.0

TianGzlab/OmicsClaw

Skill Claude CodeCodex

Complete workflow for single-cell RNA-seq analysis using Scanpy and the scverse ecosystem. Process raw data through quality control, normalization, clustering, and cell type annotation with publication-ready visualizations.

159 1mo ago A 12 tokens original Apache-2.0