bulkrna-splicing

bulkrna-splicing is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 56 tokens per session (1,018 once invoked), scanned A, original, Apache-2.0.

A summary tool for alternative splicing results from rMATS or SUPPA2, which identify different ways a gene's instructions can be joined into RNA.

In plain words
What is it for?
Use it on a prepared CSV event table to calculate ΔPSI, group events such as exon skipping and intron retention, and create filtered tables, charts, and a report.
Why use it?
It separates meaningful splicing changes from the full result table using statistical and change-size thresholds.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it on a prepared CSV event table to calculate ΔPSI, group events such as exon skipping and intron retention, and create filtered tables, charts, and a report.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/bulkrna-splicing
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill bulkrna-splicing
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bulkrna-splicing

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/bulkrna-splicing.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/bulkrna-splicing)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/bulkrna-splicing"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/bulkrna-splicing.svg" alt="Measured on agentmods" height="20"></a>
Per session 56 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,018 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 2 findings, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
  • medium analysis-evasion · line 1
    Suspicious Unicode normalization or mixed-script content
    Fix: Review the flagged content for security risks. Ensure no credentials, secrets, or sensitive data are exposed.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00056 $0.01018
Opus 5 $0.00028 $0.00509
Sonnet 5 $0.00011 $0.00204
Haiku 4.5 $0.00006 $0.00102

Measured 8d ago against content hash d7c70181b20a, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-07, from the pricing page.

Security

Grade A, and why

bulkrna-splicing scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 3 executable files (bulkrna_splicing.py, tests/__init__.py, tests/test_bulkrna_splicing.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/bulkrna/bulkrna-splicing/SKILL.md · 86 lines

How it starts

The opening of the file, as written. The whole thing — 86 lines — stays where its author put it; the contents beside it link to each section on GitHub.

bulkrna-splicing

When to use

Run AFTER rMATS or SUPPA2 has produced its splicing-event table — this skill consumes that output (not raw alignments). Computes per-event ΔPSI (delta percent-spliced-in), flags events crossing significance and ΔPSI thresholds, and groups results by event type (SE / A3SS / A5SS / MXE / RI).

Inputs & Outputs

Inputs

  • File types: .csv

Outputs

  • tables/significant_events.csv
  • tables/splicing_events.csv
  • figures/dpsi_distribution.png
  • figures/event_type_distribution.png
  • figures/volcano_splicing.png
  • report.md
  • result.json

Flow

  1. Load splicing event table. Hard-fail at bulkrna_splicing.py:365,368 on missing or invalid --input.
  2. Validate the fixed input schema: must contain columns event_type, gene, delta_psi, padj (bulkrna_splicing.py:153-155). No format detection — caller must pre-flatten rMATS / SUPPA2 output to this schema.
  3. Filter by --dpsi-cutoff AND --padj-cutoff.
  4. Group by event type; render distribution + volcano + bar plots.
  5. Emit tables/splicing_events.csv (full) + tables/significant_events.csv (filtered) + report.

Gotchas

  • This skill consumes the SPLICING TABLE, not BAM or FASTQ. Run rMATS or SUPPA2 upstream and feed their output here. The wrapper does not perform splicing detection itself — feeding it BAM files raises a parser error or silently produces an empty result.
  • --dpsi-cutoff is the ABSOLUTE value of ΔPSI. Default 0.1 keeps events with |ΔPSI| ≥ 0.1, including both inclusion-up and inclusion-down. Set to 0 to keep all directionally significant events.
  • Input schema is fixed: event_type, gene, delta_psi, padj (with optional pvalue and event_id). The script does NOT auto-detect rMATS vs SUPPA2 column conventions — if your input uses rMATS's IncLevelDifference/FDR or SUPPA2's dPSI/pval natively, rename columns first or the loader will silently drop your data.
  • Event-type breakdown depends on the upstream tool's classification. rMATS reports SE / A3SS / A5SS / MXE / RI as separate files; SUPPA2 uses an EVENT field. Concatenate / re-label these into a single event_type column before feeding the skill, or the breakdown bar chart under-counts.

Read the full file on GitHub · 86 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 86 lines · 56 tokens per session scan A d7c70181b20a

Subscribe to this mod's changes

bulkrna-splicing is a skill published in the GitHub repository TianGzlab/OmicsClaw (160 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 56 tokens to every session and 1,018 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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