genomics-epigenomics

genomics-epigenomics is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 79 tokens per session (1,160 once invoked), scanned A, original, Apache-2.0.

A tool for summarizing genomic peak files from experiments such as ATAC-seq, ChIP-seq, and CUT&Tag. Peak files mark genome regions where a signal was detected.

In plain words
What is it for?
Use it to summarize peak counts, widths, scores, and chromosome distributions from BED, narrowPeak, broadPeak, or CSV files, and produce tables and a report.
Why use it?
It provides consistent counts and measurements without requiring the tool to call peaks from raw sequencing data or handle single-cell ATAC data.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to summarize peak counts, widths, scores, and chromosome distributions from BED, narrowPeak, broadPeak, or CSV files, and produce tables and a report.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/genomics-epigenomics
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill genomics-epigenomics
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for genomics-epigenomics

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/genomics-epigenomics.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/genomics-epigenomics)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/genomics-epigenomics"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/genomics-epigenomics.svg" alt="Measured on agentmods" height="20"></a>
Per session 79 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,160 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00079 $0.01160
Opus 5 $0.00039 $0.00580
Sonnet 5 $0.00016 $0.00232
Haiku 4.5 $0.00008 $0.00116

Measured 8d ago against content hash 05e4e5647ec3, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-07, from the pricing page.

Security

Grade A, and why

genomics-epigenomics scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (genomics_epigenomics.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/genomics/genomics-epigenomics/SKILL.md · 90 lines

How it starts

The opening of the file, as written. The whole thing — 90 lines — stays where its author put it; the contents beside it link to each section on GitHub.

genomics-epigenomics

When to use

The user has a peak file (BED, narrowPeak, or broadPeak) from ATAC-seq, ChIP-seq, or CUT&Tag and wants peak summary statistics: total peak count, median / mean width, per-chromosome distribution, optional score column statistics. The script consumes peak files — it does NOT call peaks from BAM. --method (macs2 / macs3 / homer / genrich) and --assay (chip-seq / atac-seq / cut-tag) are recorded as metadata only.

For single-cell ATAC processing use scatac-preprocessing.

Inputs & Outputs

Inputs

  • Modalities: atac-seq, chip-seq
  • File types: .bed, .narrowpeak, .csv

Outputs

  • tables/peaks_per_chromosome.csv
  • tables/peaks_summary.csv
  • report.md
  • result.json

Flow

  1. Load peak file (--input <peaks.bed|narrowPeak>) or generate a demo at output_dir/demo_peaks.narrowPeak (genomics_epigenomics.py:211).
  2. Parse coordinates; compute per-peak width.
  3. Aggregate per-chromosome counts; per---assay expected-width range is added to the report (genomics_epigenomics.py:172-178).
  4. Write tables/peaks_summary.csv (genomics_epigenomics.py:352) + tables/peaks_per_chromosome.csv (:360) + report.md + result.json (:366).

Gotchas

  • No peak caller is invoked. This skill summarises an existing BED/narrowPeak file — it does NOT run MACS / Genrich. Run them upstream and feed the output here.
  • --method is metadata-only; --assay changes the report. --method is recorded in result.json only. --assay controls the per-assay expected-peak-width range injected into the summary (genomics_epigenomics.py:172-178) — chip-seq reports 200-2000 bp, atac-seq 150-500 bp, cut-tag 150-300 bp. Peak parsing itself is identical across assays.
  • --input REQUIRED unless --demo. genomics_epigenomics.py:334 raises ValueError("--input required when not using --demo"); non-existent paths raise FileNotFoundError at :337.
  • 3-column BED has no score column. Without a score (col 5 in BED6 / narrowPeak), the summary statistics for "score" are NaN. Pre-convert to narrowPeak or BED6 for score-aware stats. Note: broadPeak's "signalValue" (col 7) and qValue (col 9) are NOT read — the parser only handles up to BED6 plus the narrowPeak 10-col extension.
  • Coordinate convention is 0-based half-open (BED). Width = end - start. If your input uses 1-based closed coordinates, widths are off-by-one.
  • Demo BED has 500 fixed-pattern peaks. Useful for orchestrator smoke tests; not biologically meaningful.

Read the full file on GitHub · 90 lines

Files

What ships with it

5 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 90 lines · 79 tokens per session scan A 05e4e5647ec3

Subscribe to this mod's changes

genomics-epigenomics is a skill published in the GitHub repository TianGzlab/OmicsClaw (160 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 79 tokens to every session and 1,160 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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