genomics-sv-detection

genomics-sv-detection is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 79 tokens per session (927 once invoked), scanned A, original, Apache-2.0.

A tool for summarising structural variants in a VCF file, a standard text format for genetic differences. Structural variants are large DNA changes such as deletions, duplications, inversions, and rearrangements.

In plain words
What is it for?
Use it with an SV VCF produced by callers such as Manta, Delly, Lumpy, or Sniffles to create CSV tables, a report, and JSON results.
Why use it?
It organises existing variant-calling results by type and size instead of requiring manual VCF inspection. It does not discover variants from sequencing data.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it with an SV VCF produced by callers such as Manta, Delly, Lumpy, or Sniffles to create CSV tables, a report, and JSON results.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/genomics-sv-detection
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill genomics-sv-detection
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for genomics-sv-detection

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/genomics-sv-detection/github.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/genomics-sv-detection)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/genomics-sv-detection"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/genomics-sv-detection/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for genomics-sv-detection

Your own site · 80×15
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/genomics-sv-detection"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/genomics-sv-detection.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 79 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 927 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00079 $0.00927
Opus 5.5 $0.00032 $0.00371
Sonnet 5.5 $0.00016 $0.00185
Haiku 4.5 $0.00008 $0.00093

Measured 17d ago against content hash 4d1e339cc80f, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

genomics-sv-detection scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 17d ago.

The scan reads SKILL.md. This mod also ships 4 executable files (_api.py, examples/example_step.py, sv_detection.py, …), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/genomics/genomics-sv-detection/SKILL.md · 125 lines

How it starts

The opening of the file, as written. The whole thing — 125 lines — stays where its author put it; the contents beside it link to each section on GitHub.

genomics-sv-detection

When to use

Load this skill for the file-based analysis named in the description. The function library and CLI share the same calculations; no external aligner, assembler, caller or annotation service is started.

Use from a step

from skills._sdk.notebook import load_skill, read_input, write_output
library = load_skill("genomics-sv-detection")
data = read_input("input.vcf", reader=library.read_records)
result = library.analyze(data)
write_output(result, "tables/result.csv")
write_output(library.distribution_figure(result), "figures/distribution.png")

Run examples/example_step.py through the step runner for a small, hand-worked synthetic fixture. It asserts known summary values. The reader materializes the input in memory; use bounded FASTQ reads or pre-filter large genomic files before loading them.

API

read_records(path: str | Path) -> pd.DataFrame

Read records through read_input(path, reader=library.read_records).

:param path: Existing input file in the format documented under Inputs and outputs. :returns: Parsed records as a DataFrame. :raises ValueError: Input values or file structure cannot be parsed.

analyze(data: pd.DataFrame) -> pd.DataFrame

Compute sv-detection summaries and return a new table, leaving data unchanged.

:param data: Records containing chrom, sv_type, sv_len, filter, size_class, genotype.

:returns: Result table with diagnostics and summary in attrs['run_info']. :raises ValueError: Required columns are absent or records are empty or invalid.

run_info(data: pd.DataFrame, *, keep: bool=True) -> dict

Return the analysis diagnostics and summary.

:param data: Result returned by analyze. :param keep: Keep diagnostics by default; the CLI passes False. :returns: Independent diagnostics dictionary. :raises ValueError: analyze has not populated diagnostics.

distribution_figure(data: pd.DataFrame)

Read the full file on GitHub · 125 lines

Files

What ships with it

8 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 17d ago Changed · +37 lines · +1 tokens per session 4d1e339cc80f
  2. 1mo ago First seen · 88 lines · 78 tokens per session scan A 0f1df8c5d379

Subscribe to this mod's changes

genomics-sv-detection is a skill published in the GitHub repository TianGzlab/OmicsClaw (161 stars, last pushed 18d ago), licensed Apache-2.0. It adds 79 tokens to every session and 927 once invoked, about $0.0003 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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