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alphagenome-single-variant-analysis

alphagenome-single-variant-analysis is a skill for Claude Code, Codex from FridrichMethod/awesome-skills. It costs 118 tokens per session (2,828 once invoked), scanned A, original, no licence file.

A tool for estimating how genetic variants outside protein-coding regions may affect gene activity through the AlphaGenome API.

In plain words
What is it for?
It is for analyzing variant effects on RNA production, DNA accessibility, histone marks, and transcription-factor binding, including questions about pathogenicity and disease associations.
Why use it?
Non-coding variants can influence gene expression and the activity of DNA regions without changing a protein sequence. This helps investigate their possible biological or disease-related effects.

Skill for Claude CodeCodex

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

not rated 15repo 3d ago A scan 118 tokens custom licence

Good fit It is for analyzing variant effects on RNA production, DNA accessibility, histone marks, and transcription-factor binding, including questions about pathogenicity and disease associations.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis
View source ↗ FridrichMethod/awesome-skills
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add FridrichMethod/awesome-skills --skill alphagenome_single_variant_analysis
Clone the repo
git clone --depth 1 https://github.com/FridrichMethod/awesome-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for alphagenome-single-variant-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis/github.svg)](https://agentmods.dev/skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis)
Your own site
<a href="https://agentmods.dev/skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis"><img src="https://agentmods.dev/badge/skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for alphagenome-single-variant-analysis

Your own site · 80×15
<a href="https://agentmods.dev/skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis"><img src="https://agentmods.dev/badge/skills/fridrichmethod/awesome-skills/alphagenome_single_variant_analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 118 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,828 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00118 $0.02828
Opus 5 $0.00059 $0.01414
Sonnet 5 $0.00024 $0.00566
Haiku 4.5 $0.00012 $0.00283

Measured 6d ago against content hash a558257de284, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

alphagenome-single-variant-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

The scan reads SKILL.md. This mod also ships 7 executable files (scripts/analyze_ism.py, scripts/generate_ontology_mapping.py, scripts/interpret_splicing.py, …), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/alphagenome_single_variant_analysis/SKILL.md · 244 lines

The source is not reproduced here

A licence we could not identify

The repository carries a LICENSE file, but it is custom or dual enough that GitHub cannot name it and neither can this catalogue. Unknown terms are not permission, so the body is not copied here. Read the licence at the source and decide for yourself.

Read it on GitHub

Files

What ships with it

47 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 244 lines · 118 tokens per session scan A a558257de284

Subscribe to this mod's changes

alphagenome-single-variant-analysis is a skill published in the GitHub repository FridrichMethod/awesome-skills (15 stars, last pushed 3d ago), with no licence file. It adds 118 tokens to every session and 2,828 once invoked, about $0.0006 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

Claude CodeScientificacademic-writingagent-skillsai4scienceawesome-listbioinformatics
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