cooler-hic-matrix-summary-starter

cooler-hic-matrix-summary-starter is a skill for Claude Code, Codex from ma-compbio-lab/SkillFoundry. It costs 0 tokens per session (310 once invoked), scanned A, original, Apache-2.0.

A starter workflow for Cooler Hi-C matrices, files that store genome contact measurements used to study how DNA regions interact, with tools for inspecting small examples.

In plain words
What is it for?
It creates or reads a Cooler file and summarizes its bins, matrix shape, pixel count, and total contacts.
Why use it?
It provides a verified starting example before larger chromatin-interaction workflows are built.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit It creates or reads a Cooler file and summarizes its bins, matrix shape, pixel count, and total contacts.

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Install with agentmods
npx agentmods add skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add ma-compbio-lab/SkillFoundry --skill cooler-hic-matrix-summary-starter
Clone the repo
git clone --depth 1 https://github.com/ma-compbio-lab/SkillFoundry

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for cooler-hic-matrix-summary-starter

README.md
[![agentmods](https://agentmods.dev/badge/skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter/github.svg)](https://agentmods.dev/skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter)
Your own site
<a href="https://agentmods.dev/skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter"><img src="https://agentmods.dev/badge/skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for cooler-hic-matrix-summary-starter

Your own site · 80×15
<a href="https://agentmods.dev/skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter"><img src="https://agentmods.dev/badge/skills/ma-compbio-lab/skillfoundry/cooler-hic-matrix-summary-starter.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 0 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 310 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00000 $0.00310
Opus 5 $0.00000 $0.00155
Sonnet 5 $0.00000 $0.00062
Haiku 4.5 $0.00000 $0.00031

Measured 6d ago against content hash 21d5cef8a666, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

cooler-hic-matrix-summary-starter scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (scripts/run_cooler_hic_matrix_summary.py, tests/test_run_cooler_hic_matrix_summary.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/epigenomics-and-chromatin/cooler-hic-matrix-summary-starter/SKILL.md · 29 lines

What it actually says

cooler Hi-C Matrix Summary Starter

Use this skill to generate or inspect a tiny Hi-C contact matrix in Cooler format and summarize its bins and pixel counts in JSON.

What it does

  • Creates a deterministic toy .cool file with three bins and five nonzero upper-triangle pixels.
  • Opens the Cooler store with cooler.Cooler and summarizes matrix shape, pixel count, and total contact count.
  • Can also summarize an existing Cooler file if --input is provided.

When to use it

  • You need a runnable starter for Hi-C contact matrix formats.
  • You want a small verified example before building larger chromatin-interaction workflows.
  • You need a smoke-testable wrapper around cooler in the repo-managed scientific Python environment.

Example

slurm/envs/scientific-python/bin/python skills/epigenomics-and-chromatin/cooler-hic-matrix-summary-starter/scripts/run_cooler_hic_matrix_summary.py \
  --out scratch/epigenomics/cooler_hic_summary.json \
  --cooler-out scratch/epigenomics/toy_contacts.cool

Verification

  • Skill-local tests: python3 -m unittest discover -s skills/epigenomics-and-chromatin/cooler-hic-matrix-summary-starter/tests -p 'test_*.py'
  • Expected summary: bin_count == 3, pixel_count == 5, and total_contact_count == 38
Files

What ships with it

8 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 29 lines · 0 tokens per session scan A 21d5cef8a666

Subscribe to this mod's changes

cooler-hic-matrix-summary-starter is a skill published in the GitHub repository ma-compbio-lab/SkillFoundry (39 stars, last pushed 4mo ago), licensed Apache-2.0. It costs nothing until one of its globs matches a file; then it loads 310 tokens. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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