bio-clip-seq-clip-motif-analysis

bio-clip-seq-clip-motif-analysis is a skill for Claude Code, Codex from PKU-YuanGroup/OpenAI4S. It costs 138 tokens per session (5,871 once invoked), scanned A, a copy of bio-clip-seq-clip-motif-analysis, MIT.

A collection of methods for finding RNA sequence patterns preferred by an RNA-binding protein from CLIP-seq binding regions. CLIP-seq measures where proteins attach to RNA, while motif analysis looks for shared nearby sequences.

In plain words
What is it for?
Use it to discover and compare RNA motifs in peaks or exact crosslink sites, and to check findings against other binding datasets.
Why use it?
Binding regions alone do not explain what sequence attracts the protein. These analyses help separate real sequence preferences from biases introduced by the experiment.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to discover and compare RNA motifs in peaks or exact crosslink sites, and to check findings against other binding datasets.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add PKU-YuanGroup/OpenAI4S --skill bio-clip-seq-clip-motif-analysis
Clone the repo
git clone --depth 1 https://github.com/PKU-YuanGroup/OpenAI4S

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-clip-seq-clip-motif-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis/github.svg)](https://agentmods.dev/skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis)
Your own site
<a href="https://agentmods.dev/skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis"><img src="https://agentmods.dev/badge/skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bio-clip-seq-clip-motif-analysis

Your own site · 80×15
<a href="https://agentmods.dev/skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis"><img src="https://agentmods.dev/badge/skills/pku-yuangroup/openai4s/bio-clip-seq-clip-motif-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 138 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 5,871 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 98% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00138 $0.05871
Opus 5 $0.00069 $0.02936
Sonnet 5 $0.00028 $0.01174
Haiku 4.5 $0.00014 $0.00587

Measured 9d ago against content hash fb78a3ecae49, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

bio-clip-seq-clip-motif-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/find_motifs.sh), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

98% identical to bio-clip-seq-clip-motif-analysis — 12 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/bioskills/bio-clip-seq-clip-motif-analysis/SKILL.md · 297 lines

How it starts

The opening of the file, as written. The whole thing — 297 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Version Compatibility

Reference examples tested with: HOMER 4.11+, MEME Suite 5.5+ (STREME, MEME-ChIP, FIMO), bedtools 2.31+, kpLogo 1.1+, mCross v1+, PEKA v1+, RBPamp 0.9+, ggseqlogo 0.1+, biopython 1.83+.

Before using code patterns, verify installed versions match. If versions differ:

  • CLI: <tool> --version then <tool> --help to confirm flags
  • Python: pip show <package> then help(module.function) to check signatures

If code throws unexpected errors, introspect the installed tool and adapt the example to match the actual API rather than retrying.

CLIP-seq Motif Analysis

"Find enriched RNA motifs at my RBP binding sites" -> Discover the in vivo sequence preference of an RNA-binding protein from CLIP-seq peaks or single-nucleotide crosslink sites. The fundamental confound is the uracil bias of UV254 crosslinking: U is the most-crosslinked base, so naive motif logos centered on CL positions are U-enriched even for non-U-binding RBPs. Modern tools (mCross, PEKA) register motifs relative to the CL position and correct for this bias; legacy tools (HOMER, MEME) need careful background selection.

  • CLI (de novo, peak-based, HOMER RNA mode): findMotifs.pl peaks.fa fasta motif_out -rna -len 5,6,7,8 -p 4
  • CLI (de novo, peak-based, MEME-ChIP / STREME): streme --rna --oc streme_out -p peaks.fa -n background.fa --minw 5 --maxw 10
  • CLI (positional, single-nt CL-registered, mCross): mCross -i crosslinks.bed -g genome.fa -k 7 -o mcross_out (jointly models motif + CL position)
  • CLI (positional k-mer, no input control needed, PEKA): peka --peak_file_name peaks.bed --crosslinks_file_name crosslinks.bed --genome_file_name genome.fa --regions_file_name regions.bed --kmer_length 5 --percentile 30 --outpath peka_out (the short flags -i/-x/-g/-r/-k/-p shown in earlier docs are not all stable; use the long forms or check peka --help)
  • CLI (affinity-weighted, RBPamp): rbpamp run -i peaks.fa -k 7 -o rbpamp_out (joint affinity + motif model)
  • CLI (positional logo, kpLogo): kpLogo crosslinks_with_kmer_scores.txt -o kplogo_out (position-specific significance)

Read the full file on GitHub · 297 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 297 lines · 138 tokens per session scan A fb78a3ecae49

Subscribe to this mod's changes

bio-clip-seq-clip-motif-analysis is a skill published in the GitHub repository PKU-YuanGroup/OpenAI4S (407 stars, last pushed yesterday), licensed MIT. It adds 138 tokens to every session and 5,871 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 0 findings. It is 98% identical to bio-clip-seq-clip-motif-analysis, differing in 12 lines, and is treated as a copy.

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