534 projects whose own agent configuration covers scientific. These are not mods to install — they are how the maintainers of these repositories tell an agent what to do, and what to avoid.
All projects Building agents7,374Claude Code6,573Data and AI3,706Backend and APIs3,486Languages3,398Planning3,181Git and workflow3,100Code review2,701Memory and context2,354Testing2,311Research2,292DevOps and cloud2,282
Any agent Claude CodeCodexOpenCodeGitHub CopilotGemini CLICursorWindsurfKiro
| Project | Stars | Configures | Files | Always loaded |
|---|---|---|---|---|
| statsclaw/statsclaw statsclaw.ai A workflow framework for statistical package development | 92 | Claude Code | 2 | 25 tok |
| cyanheads/clinicaltrialsgov-mcp-server npmjs.com Search ClinicalTrials.gov trials, retrieve study details and results, and match patients t | 91 | Claude Code, Codex, OpenCode | 2 | 11,808 tok |
| IlyaGusev/academia_mcp smithery.ai Academia MCP server: Tools for automatic scientific research | 91 | Claude Code | 1 | 2,701 tok |
| tensorcircuit/tensorcircuit-ng tensorcircuit-ng.readthedocs.io Next-gen AI-native tensor-network-based quantum software framework | 89 | Claude Code, Codex, OpenCode | 12 | 1,294 tok |
| 0xSanei/darwinia colab.research.google.com The Self-Evolving Agent Ecosystem — Trading agents that evolve through Darwinian selection | 87 | Claude Code, Codex, OpenCode | 3 | 1,631 tok |
| linzhe001/Harness-Research | 86 | Claude Code, Codex | 26 | — |
| jmrplens/TFG-TFM_EPS jmrp.io Plantilla LaTeX para la elaboración de TFG y TFM en la Escuela Politécnica Superior de la | 84 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 11,314 tok |
| THU-Team-Eureka/EurekAgent EurekAgent: an autonomous research system for metric-driven tasks, built with Claude Code. | 82 | Claude Code | 4 | — |
| Lambenthan/empiricalwiki AI knowledge base for empirical research in economics and management — a complete pipeline | 82 | Claude Code, Codex, OpenCode | 31 | 4,874 tok |
| gpt-cmdr/ras-commander clbengineering.com The RAS-Commander library provides a python API and agentic features for automating HEC-RA | 79 | Claude Code, Codex, OpenCode | 71 | 2,986 tok |
| mituan-ai/PaperBanana-CN Scientific figure workbench with independent VLM/image connections, Chinese UI, and unifie | 78 | Claude Code, GitHub Copilot | 4 | 445 tok |
| jaylfc/taosmd Local-first AI memory — runs offline on any machine with 8 GB+ RAM (SBC, mini PC, laptop, | 77 | Claude Code, Codex, OpenCode | 3 | 3,177 tok |
| AMD-AGI/Apex Agents, and RL environment, for optimizing GPU kernels on AMD ROCm using LLM agents. Bench | 76 | Claude Code, Codex, OpenCode | 2 | 19,966 tok |
| dermatologist/pyomop nuchange.ca Python package for managing OHDSI clinical data models. Includes support for LLM based pla | 66 | Claude Code, Codex, OpenCode | 2 | 551 tok |
| yorkeccak/scientific-skills Natural language scientific literature search skills with semantic search over PubMed, arX | 61 | Claude Code | 1 | 78 tok |
| smsharma/clax Differentiable Boltzmann solver for cosmology in JAX | 60 | Claude Code | 1 | 5,537 tok |
| ScottDuncanAI/industrial-ai-troubleshooting-agent | 59 | Claude Code | 5 | 6,180 tok |
| jmschrei/cherimoya Cherimoya is a lightweight sequence-to-function (S2F) model that is small, fast, and easy | 59 | Claude Code | 1 | 1,098 tok |
| tabayashi0117/Score-CAM | 58 | Claude Code | 1 | 1,091 tok |
| monarch-initiative/dismech dismech.monarchinitiative.org Disease Mechanisms KB | 57 | Claude Code, Codex, GitHub Copilot, OpenCode | 29 | 39,339 tok |
| SteadfastAsArt/geoscience-skills 🌍 30 AI-powered geoscience skills for Claude Code, Cursor & GitHub Copilot. Seismic, well | 57 | Claude Code | 3 | 1,643 tok |
| jaruiz6363/OpticStudioMCPServer | 56 | Claude Code | 1 | 130 tok |
| armpro24-blip/cad-cae-copilot CAD/CAE Copilot — an AI-native CAD/CAE/CAX workbench for AI agents. Text-to-CAD, text-to-C | 56 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 36,119 tok |
| quantskills/agent-quantspace AI-native quantitative research framework | 56 | Claude Code, Codex, OpenCode | 2 | 2,304 tok |
| htlin222/robust-lit-review Automated systematic literature review pipeline generating publication-ready manuscripts f | 55 | Claude Code | 4 | 492 tok |
| traitecoevo/plant traitecoevo.github.io Trait-Driven Models of Ecology and Evolution :evergreen_tree: | 55 | Claude Code | 4 | — |
| fuwenhao12/academic-ref-inserter | 55 | Claude Code, Codex, GitHub Copilot, Cursor, Gemini CLI, OpenCode | 6 | 3,753 tok |
| fastlmm/FaST-LMM fastlmm.github.io Python version of Factored Spectrally Transformed Linear Mixed Models | 55 | Claude Code, Codex, OpenCode | 2 | 1,540 tok |
| vlasenkoalexey/tpu_performance_autoresearch_wiki vlasenkoalexey.github.io Wiki built using Karpathy method containing information about TPU performance optimization | 54 | Claude Code, Codex, Gemini CLI, OpenCode | 21 | 1,427 tok |
| qingzhoupro/afsim-skill AFSIM-SKILL is an AI coding assistant designed for the AFSIM (Advanced Framework for Model | 54 | Claude Code, Cursor | 4 | — |
| openmodelingfoundation/openmodelingfoundation.github.io openmodelingfoundation.org Website for standards and governance of the Open Modeling Foundation | 53 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 692 tok |
| MikkoVihtakari/ggOceanMaps Plot oceanographic research data on maps using ggplot2 | 53 | Claude Code, Codex, OpenCode | 2 | 5,032 tok |
| whanyu1212/QuantRL-Lab whanyu1212.github.io Reinforcement Learning Testbed for Quantitative Trading | 53 | Claude Code, Codex, OpenCode | 2 | 6,821 tok |
| wanghao9610/STAR wanghao9610.github.io STAR: Systematic Toolchain for AI Research (Harness, WIP) | 51 | Claude Code, Codex, OpenCode | 27 | 1,754 tok |
| clefru/ocrmypdf-paddleocr PaddleOCR plugin for OCRmyPDF. | 51 | Claude Code | 1 | 2,132 tok |
| Synthyra/FastPLMs Easy to use and efficient implementations of Protein Language Models | 51 | Claude Code, Codex, OpenCode | 2 | 2,041 tok |
| oqtopus-team/qdash oqtopus-team.github.io QDash: Large-scale QPU Calibration Platform | 51 | Claude Code, Codex, OpenCode | 3 | 2,453 tok |
| jamalrfordii-arch/Vanguard-Map jamalrfordii-arch.github.io 3D multi-domain tactical intelligence map — live ships, flights, satellites, cables & spac | 50 | Claude Code | 1 | 5,129 tok |
| ElliotXie/autozyme autozyme.com Autonomous multi-agent framework to optimize scientific software | 50 | Claude Code | 1 | 289 tok |
| cqframework/clinical-reasoning cqframework.org CQF Clinical Reasoning on FHIR for Java | 49 | Claude Code, Codex, OpenCode | 3 | 930 tok |
| openscientist-io/openscientist AI co-scientist | 49 | Claude Code | 1 | 1,566 tok |
| xi-zhao/OpenQuantum Open-source quantum Agent workspace with a desktop client, Web UI, messaging, Qiskit/MCP t | 48 | Claude Code, Codex, OpenCode | 12 | 3,150 tok |
| steel-dev/leaderboard leaderboard.steel.dev Open leaderboard for browser agents | 48 | Claude Code, Codex, OpenCode | 2 | 630 tok |
| life-itself/climate climate.lifeitself.org 🌍🔥 Life Itself's ongoing inquiry into the climate crisis | 48 | Claude Code, Codex, OpenCode | 4 | 1,196 tok |
| schildep/verified-polygon-intersection schildep.github.io Formally verified polygon intersection | 48 | Claude Code | 2 | 746 tok |
| csml-rpi/AI-CFD-Scientist | 48 | Claude Code, Codex, OpenCode | 2 | 4,178 tok |
| jiegec/waveform-mcp MCP server to read waveform files | 47 | Claude Code | 1 | 958 tok |
| cafferychen777/ChatSpatial docs.cafferyang.com MCP server for spatial transcriptomics analysis through natural language interfaces. | 44 | Claude Code | 9 | — |
| Eden-Kramer-Lab/ripple_detection Tools for identifying sharp wave ripple events using LFPs | 43 | Claude Code | 1 | 3,134 tok |
| letitbk/claude-academic-setup Claude Code + Cursor setup for academic social science researchers (R, Stata, Python). 22 | 43 | Claude Code, Codex, OpenCode | 2 | 805 tok |