sdrf-cellline

sdrf-cellline is a skill for Claude Code from bigbio/sdrf-skills. It costs 82 tokens per session (4,111 once invoked), scanned A, original, MIT.

A workflow for looking up cell-line information and adding it to an SDRF, a metadata file for proteomics experiments. Cell lines are laboratory-grown populations of cells.

In plain words
What is it for?
Use it for names such as HeLa or MCF-7, Cellosaurus identifiers, and requests to annotate cell-line characteristics in an SDRF.
Why use it?
It supplies verified information such as organism, disease, sex, tissue site, ancestry, and age instead of relying on guesses.

Skill for Claude Code

Written for Claude Code: user-invocable in frontmatter.

Part of the sdrf-skills plugin — 16 skills, 2 hooks, 1 MCP server shipped together

Good fit Use it for names such as HeLa or MCF-7, Cellosaurus identifiers, and requests to annotate cell-line characteristics in an SDRF.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/bigbio/sdrf-skills/sdrf-cellline
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add bigbio/sdrf-skills --skill sdrf-cellline
Clone the repo
git clone --depth 1 https://github.com/bigbio/sdrf-skills

Made for: Claude Code.

Or install sdrf-skills, the plugin that ships this one along with the rest of its 16 skills, 2 hooks, 1 MCP server.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for sdrf-cellline

README.md
[![agentmods](https://agentmods.dev/badge/skills/bigbio/sdrf-skills/sdrf-cellline/github.svg)](https://agentmods.dev/skills/bigbio/sdrf-skills/sdrf-cellline)
Your own site
<a href="https://agentmods.dev/skills/bigbio/sdrf-skills/sdrf-cellline"><img src="https://agentmods.dev/badge/skills/bigbio/sdrf-skills/sdrf-cellline/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for sdrf-cellline

Your own site · 80×15
<a href="https://agentmods.dev/skills/bigbio/sdrf-skills/sdrf-cellline"><img src="https://agentmods.dev/badge/skills/bigbio/sdrf-skills/sdrf-cellline.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 82 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,111 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 6 findings, up to medium

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • medium Data Exfiltration · line 22
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 23
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 93
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 96
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 97
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 100
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00082 $0.04111
Opus 5 $0.00041 $0.02056
Sonnet 5 $0.00016 $0.00822
Haiku 4.5 $0.00008 $0.00411

Measured 4d ago against content hash dde13c54bae0, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

sdrf-cellline scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 4d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

curl -sSLO https://ftp.expasy.org/databases/cellosaurus/cellosaurus.txt
skills/sdrf-cellline/SKILL.md · 317 lines

How it starts

The opening of the file, as written. The whole thing — 317 lines — stays where its author put it; the contents beside it link to each section on GitHub.

SDRF Cell Line Annotation

You are translating cell line identity into the SDRF columns required by the cell-lines template. The source of truth is Cellosaurus (SIB / Expasy) — it is not hosted on EBI OLS, so this skill queries Cellosaurus directly. OLS is still used for the target ontologies the SDRF columns reference (NCBITaxon, MONDO, UBERON, HANCESTRO, CLO/BTO/EFO). This skill encodes the rules for the translation — it does not ship a local database.

Cellosaurus access

Mode Endpoint / file Notes
Web (browse) https://www.cellosaurus.org/<CVCL_id> Human-readable record.
REST API (JSON) https://api.cellosaurus.org/cell-line/<CVCL_id>?format=json Single-entry fetch; preferred for accession lookups.
REST search https://api.cellosaurus.org/search/cell-line?q=<query>&format=json Free-text / field-qualified search (id:HeLa, sy:HeLa-S3).
Bulk download https://ftp.expasy.org/databases/cellosaurus/cellosaurus.txt (flat) https://ftp.expasy.org/databases/cellosaurus/cellosaurus.obo (OBO) https://ftp.expasy.org/databases/cellosaurus/cellosaurus.xml (XML) Offline / batch use only. Re-download monthly to stay current.

Use the REST API by default. Drop to the bulk file only when the user asks for offline mode or needs to enrich many SDRFs in one pass.

When to Use

  • A single cell line lookup ("What is HeLa?" / "Look up CVCL_0030").
  • Enriching an SDRF where characteristics[cell line] is filled but the Cellosaurus-derivable columns (organism, disease, sampling site, sex, ancestry, age, developmental stage, cellosaurus accession/name) are blank, generic, or inconsistent.
  • Resolving ambiguous cell line names raised by /sdrf-skills:sdrf-annotate, /sdrf-skills:sdrf-validate, or /sdrf-skills:sdrf-fix.

For pure ontology-term lookup unrelated to cell lines, use /sdrf-skills:sdrf-knowledge.

Step 0: Identify the cell-lines template requirements

Always read the template first — column names, requirement levels, and target ontologies must come from the spec, never from memory.

Read the full file on GitHub · 317 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 4d ago Changed · -1 tokens per session dde13c54bae0
  2. 10d ago First seen · 317 lines · 83 tokens per session scan A 85afb85b4f52

Subscribe to this mod's changes

sdrf-cellline is a skill published in the GitHub repository bigbio/sdrf-skills (18 stars, last pushed 4d ago), licensed MIT. It adds 82 tokens to every session and 4,111 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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