sc-cell-communication

sc-cell-communication is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 69 tokens per session (2,057 once invoked), scanned A, original, Apache-2.0.

A single-cell analysis that estimates communication between labelled cell types by looking for matching signals sent by one cell type and received by another. These signals are called ligand–receptor interactions.

In plain words
What is it for?
Use it on annotated single-cell data to study sender–receiver relationships, such as communication between immune and tumour cells. It is for cell communication, not for assigning cell-type labels or building transcription-factor networks.
Why use it?
It can be difficult to identify which cell types may influence one another from gene-expression data alone. The results provide interaction tables and, with some methods, pathway or network summaries.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it on annotated single-cell data to study sender–receiver relationships, such as…

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/sc-cell-communication
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill sc-cell-communication
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for sc-cell-communication

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-cell-communication.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-cell-communication)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-cell-communication"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-cell-communication.svg" alt="Measured on agentmods" height="20"></a>
Per session 69 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,057 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00069 $0.02057
Opus 5 $0.00034 $0.01028
Sonnet 5 $0.00014 $0.00411
Haiku 4.5 $0.00007 $0.00206

Measured 3d ago against content hash 3f351919ac19, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-06, from the pricing page.

Security

Grade A, and why

sc-cell-communication scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 3d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (sc_cell_communication.py, tests/test_sc_cell_communication.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/singlecell/scrna/sc-cell-communication/SKILL.md · 154 lines

How it starts

The opening of the file, as written. The whole thing — 154 lines — stays where its author put it; the contents beside it link to each section on GitHub.

sc-cell-communication

When to use

The user has an annotated scRNA AnnData (cell-type labels in obs["cell_type"] or another column passed via --cell-type-key) and wants ligand-receptor / sender-receiver interaction tables and figures. Five backends:

  • builtin (default) — compact curated L-R set, heuristic score, no p-values.
  • liana — Python LIANA rank aggregation (recommended general default).
  • cellphonedb — official CellPhoneDB statistical workflow (human-only).
  • cellchat_r — R-backed CellChat with pathway / centrality outputs.
  • nichenet_r — R-backed NicheNet ligand prioritisation; needs explicit --receiver + --senders + --condition-* (human-only).

For TF → target gene regulatory networks use sc-grn. For cell-type labelling use sc-cell-annotation.

Inputs & Outputs

Inputs

  • Modalities: scrna
  • File types: .h5ad
  • Requires a preprocessed AnnData (X normalised, PCA/neighbours present)

Outputs

  • tables/_matrix.csv
  • tables/cellchat_centrality.csv
  • tables/cellchat_count_matrix.csv
  • tables/cellchat_pathways.csv
  • tables/cellchat_results.csv
  • tables/cellchat_weight_matrix.csv
  • tables/cellphonedb_means.csv
  • tables/cellphonedb_pvalues.csv
  • tables/cellphonedb_significant_means.csv
  • tables/group_role_summary.csv
  • tables/lr_interactions.csv
  • tables/meta.tsv
  • tables/nichenet_ligand_activities.csv
  • tables/nichenet_ligand_receptors.csv
  • tables/nichenet_ligand_target_links.csv
  • tables/nichenet_lr_network.csv
  • tables/pathway_summary.csv
  • tables/sender_receiver_summary.csv
  • tables/top_interactions.csv
  • figures/r_ccc_bipartite.png
  • figures/r_ccc_bubble.png
  • figures/r_ccc_diff_network.png
  • figures/r_ccc_heatmap.png
  • figures/r_ccc_network.png
  • figures/r_ccc_stat_bar.png
  • figures/r_ccc_stat_scatter.png
  • figures/r_ccc_stat_violin.png
  • input.h5ad
  • processed.h5ad
  • report.md
  • result.json
  • Processed AnnData (saves_h5ad)

Read the full file on GitHub · 154 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 3d ago First seen · 154 lines · 69 tokens per session scan A 3f351919ac19

Subscribe to this mod's changes

sc-cell-communication is a skill published in the GitHub repository TianGzlab/OmicsClaw (160 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 69 tokens to every session and 2,057 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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