sc-count

sc-count is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 62 tokens per session (1,453 once invoked), scanned A, original, Apache-2.0.

A processing step that turns single-cell sequencing reads or existing counting-tool output into per-cell gene counts in a standard AnnData file. FASTQ files are the raw sequencing files containing the reads.

In plain words
What is it for?
Use it when starting with FASTQ files or output from tools such as Cell Ranger, STARsolo, SimpleAF, or kallisto|bustools. It prepares data for quality control, merging, and analysis.
Why use it?
Different counting tools produce different layouts and formats, making downstream analysis difficult to standardise. This creates a consistent input for later single-cell workflows.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it when starting with FASTQ files or output from tools such as Cell Ranger, STARsolo, SimpleAF, or kallisto|bustools. It prepares data for quality control, merging, and analysis.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/sc-count
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill sc-count
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for sc-count

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-count/github.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-count)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-count"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-count/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for sc-count

Your own site · 80×15
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-count"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-count.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 62 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,453 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00062 $0.01453
Opus 5 $0.00031 $0.00727
Sonnet 5 $0.00012 $0.00291
Haiku 4.5 $0.00006 $0.00145

Measured 5d ago against content hash b2ff6fdd602a, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

sc-count scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 5d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (sc_count.py, tests/test_sc_count.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/singlecell/scrna/sc-count/SKILL.md · 130 lines

How it starts

The opening of the file, as written. The whole thing — 130 lines — stays where its author put it; the contents beside it link to each section on GitHub.

sc-count

When to use

The user has FASTQ files (or pre-existing tool output directories) and wants per-cell counts in OmicsClaw's canonical AnnData contract. Four backends share one CLI: cellranger, starsolo, simpleaf, kb-python. When passed an already-counted directory the skill re-canonicalises rather than re-counts. Pairs with sc-fastq-qc upstream (read QC) and sc-multi-count downstream (merging multiple samples).

Inputs & Outputs

Inputs

  • Input kinds: file, directory
  • Modalities: scrna
  • File types: .fastq, .fq, .h5ad
  • FASTQ structure: valid first record; paired layout
  • Directory layouts (any): paired-fastq, tenx-matrix, cellranger-output, starsolo-output, pseudoalign-output

Outputs

  • tables/Summary.csv
  • tables/backend_summary.csv
  • tables/barcode_metrics.csv
  • tables/barcodes.tsv
  • tables/cell_metadata.csv
  • tables/count_summary.csv
  • tables/features.tsv
  • tables/genes.tsv
  • tables/metrics_summary.csv
  • tables/simpleaf_t2g.tsv
  • figures/barcode_rank.png
  • figures/count_complexity_scatter.png
  • figures/count_distributions.png
  • 3M-february-2018.txt
  • 737K-august-2016.txt
  • Aligned.sortedByCoord.out.bam
  • analysis_summary.txt
  • cells_x_genes.barcodes.txt
  • cells_x_genes.genes.txt
  • multiqc_report.html
  • possorted_genome_bam.bam
  • processed.h5ad
  • quants_mat_cols.txt
  • quants_mat_rows.txt
  • simpleaf_index.json
  • standardized_input.h5ad
  • web_summary.html
  • report.md
  • result.json
  • Processed AnnData (saves_h5ad)

Flow

  1. Resolve --input; if it's an existing CellRanger / STARsolo / SimpleAF / kb-python output dir, re-canonicalise instead of running the backend.
  2. Otherwise validate backend prerequisites (chemistry, reference, t2g for kb-python, whitelist for STARsolo).
  3. Run the chosen backend against the FASTQ (and --read2 if explicit).
  4. Load the resulting matrix into AnnData; canonicalise (layers["counts"], adata.raw, gene-name harmonisation).
  5. Render barcode-rank + count-distribution figures.
  6. Emit processed.h5ad + report.md + result.json.

Read the full file on GitHub · 130 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 5d ago First seen · 130 lines · 62 tokens per session scan A b2ff6fdd602a

Subscribe to this mod's changes

sc-count is a skill published in the GitHub repository TianGzlab/OmicsClaw (160 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 62 tokens to every session and 1,453 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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