sc-cytotrace

sc-cytotrace is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 63 tokens per session (1,364 once invoked), scanned A, original, Apache-2.0.

A single-cell analysis that gives each cell a score representing its likely differentiation potency, from more differentiated to more stem-like. It estimates this from the number of genes detected in each cell.

In plain words
What is it for?
Use it on normalised or raw-count single-cell data to compare differentiation potential across cells or groups. It is for potency scoring, not for ordering cells along a trajectory or assigning cell types.
Why use it?
Cell populations can differ in how mature or stem-like they appear, but that pattern is not always clear from clusters alone. A per-cell score and label make the pattern easier to compare.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it on normalised or raw-count single-cell data to compare differentiation potential across cells or groups. It is for potency scoring, not for ordering cells along a trajectory or assigning cell types.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/sc-cytotrace
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill sc-cytotrace
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for sc-cytotrace

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-cytotrace/github.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-cytotrace)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-cytotrace"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-cytotrace/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for sc-cytotrace

Your own site · 80×15
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-cytotrace"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-cytotrace.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 63 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,364 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00063 $0.01364
Opus 5 $0.00032 $0.00682
Sonnet 5 $0.00013 $0.00273
Haiku 4.5 $0.00006 $0.00136

Measured 8d ago against content hash b1227075829c, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

sc-cytotrace scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (sc_cytotrace.py, tests/test_sc_cytotrace_methods.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/singlecell/scrna/sc-cytotrace/SKILL.md · 114 lines

How it starts

The opening of the file, as written. The whole thing — 114 lines — stays where its author put it; the contents beside it link to each section on GitHub.

sc-cytotrace

When to use

The user has a normalised (or raw-count) scRNA AnnData and wants a single per-cell differentiation potency score (0 = differentiated, 1 = stem/totipotent), plus a 6-bin categorical label (Differentiated, Mostly Differentiated, ..., Totipotent). The implementation uses the CytoTRACE-simple proxy: gene-expression complexity (number of genes detected per cell), KNN-smoothed and rank- normalised. Single backend: cytotrace_simple.

Output goes into obs["cytotrace_score"], obs["cytotrace_potency"], obs["cytotrace_gene_count"]. For trajectory ordering use sc-pseudotime; for cell-type labels use sc-cell-annotation.

Inputs & Outputs

Inputs

  • Modalities: scrna
  • File types: .h5ad
  • Requires a preprocessed AnnData (X normalised, PCA/neighbours present)

Outputs

  • tables/cell_metadata.csv
  • tables/cytotrace_embedding.csv
  • tables/cytotrace_scores.csv
  • figures/potency_composition.png
  • figures/potency_umap.png
  • figures/r_cell_density.png
  • figures/r_cytotrace_boxplot.png
  • figures/r_embedding_discrete.png
  • figures/r_embedding_feature.png
  • figures/score_distribution.png
  • analysis_summary.txt
  • processed.h5ad
  • report.md
  • result.json
  • Processed AnnData (saves_h5ad) — adds obs: cytotrace_score, cytotrace_potency, cytotrace_gene_count

Flow

  1. Load AnnData; preflight requires .X to be normalized_expression OR raw_counts (matrix-contract check).
  2. Compute per-cell gene-count complexity (number of detected genes).
  3. Rank-normalise gene counts; KNN-smooth across --n-neighbors neighbours.
  4. Min-max rescale to [0, 1]cytotrace_score.
  5. Bin score into 6 potency categories; record counts per category.
  6. Detect degenerate output (≤ 1 unique category) → write result.json["suggested_actions"]; do NOT raise.
  7. Render figures, save tables, processed.h5ad, report.md, result.json.

Read the full file on GitHub · 114 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 114 lines · 63 tokens per session scan A b1227075829c

Subscribe to this mod's changes

sc-cytotrace is a skill published in the GitHub repository TianGzlab/OmicsClaw (160 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 63 tokens to every session and 1,364 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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