spatial-communication

spatial-communication is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 57 tokens per session (1,313 once invoked), scanned A, original, Apache-2.0.

A workflow for estimating communication between labelled cell types in spatial transcriptomics using ligand-receptor pairs. Ligands are signalling molecules released by one cell, while receptors are molecules that can receive those signals on another cell.

In plain words
What is it for?
Use it to score ligand-receptor interactions, compare communication patterns, and export interaction, pathway, and cell-centrality tables.
Why use it?
It helps identify which cell-type pairs may be sending and receiving signals in tissue while taking their spatial dataset and labels into account.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to score ligand-receptor interactions, compare communication patterns, and export interaction, pathway, and cell-centrality tables.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/spatial-communication
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill spatial-communication
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for spatial-communication

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/spatial-communication/github.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/spatial-communication)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/spatial-communication"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/spatial-communication/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for spatial-communication

Your own site · 80×15
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/spatial-communication"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/spatial-communication.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 57 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,313 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00057 $0.01313
Opus 5.5 $0.00023 $0.00525
Sonnet 5.5 $0.00011 $0.00263
Haiku 4.5 $0.00006 $0.00131

Measured 17d ago against content hash 0aa7bd4f2204, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

spatial-communication scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 17d ago.

The scan reads SKILL.md. This mod also ships 6 executable files (_api.py, examples/example_step.py, spatial_communication.py, …), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/spatial/spatial-communication/SKILL.md · 128 lines

How it starts

The opening of the file, as written. The whole thing — 128 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Spatial communication

When to use

Infer ligand-receptor interactions between annotated populations. LIANA is the default; CellPhoneDB and FastCCC need a local CellPhoneDB database. CellChat runs in an R subprocess. These methods do not constrain interactions by spatial distance: coordinates support the CLI maps, not the inference.

API

Use load_skill("spatial-communication") in an analysis step. examples/example_step.py uses real PBMC expression with explicitly synthetic coordinates. The CLI demo uses synthetic expression and is not biological evidence.

communicate(adata, *, method='liana', cell_type_key='leiden', species='human', random_state=None, **parameters)

Infer ligand-receptor interactions and return the same AnnData.

LIANA uses raw when present, otherwise X. Other backends read normalized X. Coordinates support CLI maps; these methods do not impose distance filters.

:param adata: Log-normalized expression with cell-type labels; modified in place. :param method: CLI default liana; cellphonedb, fastccc or cellchat_r also supported. :param cell_type_key: CLI default leiden; obs column defining populations. :param species: CLI default human; mouse supported by LIANA and CellChat. :param random_state: None keeps LIANA seed 1337 and CellChat seed 1; CellPhoneDB uses 0. :param parameters: Native backend keywords in references/parameters.md. :returns: The same AnnData with canonical ccc_results and role summaries in uns. :raises ValueError: Method, labels, species or numeric controls are invalid. :raises ImportError: Optional backend is missing; use install_skill_deps. :raises FileNotFoundError: CellPhoneDB/FastCCC's local database is missing.

interactions(adata, *, significant_only=False)

Return ligand-receptor scores; unmeasured p values remain missing.

:param adata: AnnData returned by communicate. :param significant_only: Default False; True selects real p values below 0.05. :returns: A new DataFrame with ligand, receptor, source, target, score and pvalue. :raises ValueError: No run is recorded.

Read the full file on GitHub · 128 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 17d ago Changed · -21 lines · -25 tokens per session 0aa7bd4f2204
  2. 1mo ago First seen · 149 lines · 82 tokens per session scan A dfe6345bc8c6

Subscribe to this mod's changes

spatial-communication is a skill published in the GitHub repository TianGzlab/OmicsClaw (161 stars, last pushed 17d ago), licensed Apache-2.0. It adds 57 tokens to every session and 1,313 once invoked, about $0.0002 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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