671 projects whose own agent configuration covers scientific. These are not mods to install — they are how the maintainers of these repositories tell an agent what to do, and what to avoid.
All projects Building agents7,374Claude Code6,573Data and AI3,706Backend and APIs3,486Languages3,398Planning3,181Git and workflow3,100Code review2,701Memory and context2,354Testing2,311Research2,292DevOps and cloud2,282
Any agent Claude CodeCodexOpenCodeGitHub CopilotGemini CLICursorWindsurfKiro
| Project | Stars | Configures | Files | Always loaded |
|---|---|---|---|---|
| smsharma/clax Differentiable Boltzmann solver for cosmology in JAX | 60 | Claude Code | 1 | 5,537 tok |
| ScottDuncanAI/industrial-ai-troubleshooting-agent | 59 | Claude Code | 5 | 6,180 tok |
| jmschrei/cherimoya Cherimoya is a lightweight sequence-to-function (S2F) model that is small, fast, and easy | 59 | Claude Code | 1 | 1,098 tok |
| tabayashi0117/Score-CAM | 58 | Claude Code | 1 | 1,091 tok |
| monarch-initiative/dismech dismech.monarchinitiative.org Disease Mechanisms KB | 57 | Claude Code, Codex, GitHub Copilot, OpenCode | 29 | 39,339 tok |
| SteadfastAsArt/geoscience-skills 🌍 30 AI-powered geoscience skills for Claude Code, Cursor & GitHub Copilot. Seismic, well | 57 | Claude Code | 3 | 1,643 tok |
| jaruiz6363/OpticStudioMCPServer | 56 | Claude Code | 1 | 130 tok |
| armpro24-blip/cad-cae-copilot CAD/CAE Copilot — an AI-native CAD/CAE/CAX workbench for AI agents. Text-to-CAD, text-to-C | 56 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 36,119 tok |
| quantskills/agent-quantspace AI-native quantitative research framework | 56 | Claude Code, Codex, OpenCode | 2 | 2,304 tok |
| htlin222/robust-lit-review Automated systematic literature review pipeline generating publication-ready manuscripts f | 55 | Claude Code | 4 | 492 tok |
| traitecoevo/plant traitecoevo.github.io Trait-Driven Models of Ecology and Evolution :evergreen_tree: | 55 | Claude Code | 4 | — |
| fuwenhao12/academic-ref-inserter | 55 | Claude Code, Codex, GitHub Copilot, Cursor, Gemini CLI, OpenCode | 6 | 3,753 tok |
| fastlmm/FaST-LMM fastlmm.github.io Python version of Factored Spectrally Transformed Linear Mixed Models | 55 | Claude Code, Codex, OpenCode | 2 | 1,540 tok |
| CliMA/CloudMicrophysics.jl clima.github.io GPU-capable cloud microphysics and aerosol parameterizations for the CliMA Earth System Mo | 55 | Codex, OpenCode | 1 | 989 tok |
| vlasenkoalexey/tpu_performance_autoresearch_wiki vlasenkoalexey.github.io Wiki built using Karpathy method containing information about TPU performance optimization | 54 | Claude Code, Codex, Gemini CLI, OpenCode | 21 | 1,427 tok |
| qingzhoupro/afsim-skill AFSIM-SKILL is an AI coding assistant designed for the AFSIM (Advanced Framework for Model | 54 | Claude Code, Cursor | 4 | — |
| openmodelingfoundation/openmodelingfoundation.github.io openmodelingfoundation.org Website for standards and governance of the Open Modeling Foundation | 53 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 692 tok |
| MikkoVihtakari/ggOceanMaps Plot oceanographic research data on maps using ggplot2 | 53 | Claude Code, Codex, OpenCode | 2 | 5,032 tok |
| whanyu1212/QuantRL-Lab whanyu1212.github.io Reinforcement Learning Testbed for Quantitative Trading | 53 | Claude Code, Codex, OpenCode | 2 | 6,821 tok |
| wanghao9610/STAR wanghao9610.github.io STAR: Systematic Toolchain for AI Research (Harness, WIP) | 51 | Claude Code, Codex, OpenCode | 27 | 1,754 tok |
| clefru/ocrmypdf-paddleocr PaddleOCR plugin for OCRmyPDF. | 51 | Claude Code | 1 | 2,132 tok |
| Synthyra/FastPLMs Easy to use and efficient implementations of Protein Language Models | 51 | Claude Code, Codex, OpenCode | 2 | 2,041 tok |
| oqtopus-team/qdash oqtopus-team.github.io QDash: Large-scale QPU Calibration Platform | 51 | Claude Code, Codex, OpenCode | 3 | 2,453 tok |
| jamalrfordii-arch/Vanguard-Map jamalrfordii-arch.github.io 3D multi-domain tactical intelligence map — live ships, flights, satellites, cables & spac | 50 | Claude Code | 1 | 5,129 tok |
| ElliotXie/autozyme autozyme.com Autonomous multi-agent framework to optimize scientific software | 50 | Claude Code | 1 | 289 tok |
| agjs/gb10-clock-cap Capping GPU clocks on NVIDIA GB10: -12C peak temp, -36% GPU power, ~1.6% throughput cost. | 50 | Codex, OpenCode | 1 | 1,319 tok |
| cqframework/clinical-reasoning cqframework.org CQF Clinical Reasoning on FHIR for Java | 49 | Claude Code, Codex, OpenCode | 3 | 930 tok |
| openscientist-io/openscientist AI co-scientist | 49 | Claude Code | 1 | 1,566 tok |
| Dicklesworthstone/frankensim Plan-first Rust continuum for certified geometry, physics simulation, optimization, and re | 49 | Codex, OpenCode | 1 | 9,289 tok |
| xi-zhao/OpenQuantum Open-source quantum Agent workspace with a desktop client, Web UI, messaging, Qiskit/MCP t | 48 | Claude Code, Codex, OpenCode | 12 | 3,150 tok |
| AbhiRawat4841/mathematica-mcp Model Context Protocol (MCP) server that connects AI agents (Claude, Cursor, etc.) to Wolf | 48 | Codex, OpenCode | 1 | 533 tok |
| steel-dev/leaderboard leaderboard.steel.dev Open leaderboard for browser agents | 48 | Claude Code, Codex, OpenCode | 2 | 630 tok |
| life-itself/climate climate.lifeitself.org 🌍🔥 Life Itself's ongoing inquiry into the climate crisis | 48 | Claude Code, Codex, OpenCode | 4 | 1,196 tok |
| schildep/verified-polygon-intersection schildep.github.io Formally verified polygon intersection | 48 | Claude Code | 2 | 746 tok |
| csml-rpi/AI-CFD-Scientist | 48 | Claude Code, Codex, OpenCode | 2 | 4,178 tok |
| jvogan/motif jvogan.github.io An AI-native molecular biology workbench for Claude Science: Claude opens sequence files a | 47 | Codex, OpenCode | 1 | 984 tok |
| jiegec/waveform-mcp MCP server to read waveform files | 47 | Claude Code | 1 | 958 tok |
| Jyx0208/claude-science-api-bridge A local macOS proxy and installer that connects Claude Science to third-party APIs such as | 46 | Codex, OpenCode | 1 | 1,090 tok |
| cafferychen777/ChatSpatial docs.cafferyang.com MCP server for spatial transcriptomics analysis through natural language interfaces. | 44 | Claude Code | 9 | — |
| soo-jeongkim/co-pymol PyMOL plugin - drive PyMOL from Claude Code, Cursor, or any MCP client. | 44 | Codex, OpenCode | 1 | 3,921 tok |
| Eden-Kramer-Lab/ripple_detection Tools for identifying sharp wave ripple events using LFPs | 43 | Claude Code | 1 | 3,134 tok |
| letitbk/claude-academic-setup Claude Code + Cursor setup for academic social science researchers (R, Stata, Python). 22 | 43 | Claude Code, Codex, OpenCode | 2 | 805 tok |
| QinxiangCao/QualifiedCProgramming QCP (Qualified C Programming), a C program verification tool | 43 | Claude Code, Codex, OpenCode | 7 | 4,998 tok |
| alti3/stk-mcp An MCP server allowing LLMs to interact with Ansys/AGI STK - Digital Mission Engineering S | 42 | Codex, OpenCode | 1 | 288 tok |
| LaplaceYoung/ansys-aedt-mcp MCP server for Ansys Electronics Desktop automation with PyAEDT, HFSS, Maxwell, Q3D, Icepa | 42 | Codex, OpenCode | 1 | 182 tok |
| dhicoc/wuyun-liuqi-skills Five Movements and Six Qi Skills Router — AI auto-routing + deterministic calculation engi | 41 | Claude Code, Codex, OpenCode | 3 | 1,562 tok |
| piebro/openstreetmap-statistics piebro.github.io Monthly updated interactive statistics about OpenStreetMap. | 40 | Codex, OpenCode | 1 | 5,736 tok |
| Karel0001/old-school-academic-writer | 40 | Claude Code | 1 | — |
| voxel51/fiftyone-skills | 39 | Codex, OpenCode | 1 | 5,844 tok |
| Katagiri-Hoshino-Lab/VibeCodeHPC CLI-based multi-agents for Auto-Tuning (e.g. HPC code optimazation loops) supporting Local | 39 | Claude Code | 1 | 1,693 tok |