671 projects whose own agent configuration covers scientific. These are not mods to install — they are how the maintainers of these repositories tell an agent what to do, and what to avoid.
All projects Building agents7,374Claude Code6,573Data and AI3,706Backend and APIs3,486Languages3,398Planning3,181Git and workflow3,100Code review2,701Memory and context2,354Testing2,311Research2,292DevOps and cloud2,282
Any agent Claude CodeCodexOpenCodeGitHub CopilotGemini CLICursorWindsurfKiro
| Project | Stars | Configures | Files | Always loaded |
|---|---|---|---|---|
| psu-efd/pyHMT2D Python Hydraulic Modeling Tools - 2D | 130 | Claude Code, Codex, OpenCode | 11 | 2,924 tok |
| NVlabs/ASPIRE ASPIRE: Agentic /Skills Discovery for Robotics | 127 | Claude Code, Codex, OpenCode | 2 | 1,405 tok |
| iancanderson/openscad-agent A Claude Code-powered 3D modeling agent environment for creating 3D printable designs usin | 126 | Claude Code | 4 | 810 tok |
| CliMA/ClimaAtmos.jl clima.github.io GPU-capable global atmosphere model of the CliMA Earth System Model, designed for calibrat | 126 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 905 tok |
| xingwudao/open-xquant xingwudao.github.io AI quantitative research framework: AI Agent-driven strategy backtesting, factor research, | 126 | Claude Code, Codex, OpenCode | 2 | 1,019 tok |
| voidful/academic-skills A complete academic research Skill suite. Supports Claude Code, ChatGPT / Codex CLI, and G | 126 | Claude Code | 1 | 709 tok |
| DrugClaw/DrugClaw drugclaw.com 💊 AI Research Assistant for Accelerated Drug Discovery. 🦞 | 125 | Claude Code, Codex, OpenCode | 2 | 3,050 tok |
| evo-design/proto-tools proto.evodesign.org A universal infrastructure layer for generative biology | 125 | Claude Code, Codex, Gemini CLI, OpenCode | 5 | 1,593 tok |
| CliMA/EnsembleKalmanProcesses.jl clima.github.io Derivative-free parameter calibration and uncertainty quantification for expensive models | 124 | Claude Code | 8 | — |
| genggng/hermes-arxiv-agent genggng.github.io An agent skill based on Hermes: automatically fetches papers from arXiv daily, uses AI to | 119 | Codex, OpenCode | 1 | 2,050 tok |
| dreadnode/agent-lens dreadnode.github.io Agent observability and replay tooling for AI safety & interpretability research. | 115 | Claude Code, Codex | 2 | 2,762 tok |
| 001TMF/blatant-why AI-powered biologics design campaign agent — multi-agent orchestration with BoltzGen, PXDe | 114 | Claude Code | 6 | 634 tok |
| diegoscarabelli/garmin-health-data pypi.org A simple Python CLI to download Garmin Connect data as local files and load them into a SQ | 114 | Claude Code | 1 | 1,240 tok |
| nudt-sawlab/PiLoT Code for "PiLoT: Neural Pixel-to-3D Registration for UAV-based Ego and Target Geo-localiza | 113 | Codex, OpenCode | 1 | 1,239 tok |
| share-skills/pi share-skills.github.io PI（π）—— When The Art of War Meets Cognitive Science for Ai | 108 | Claude Code | 1 | 409 tok |
| celeritas-project/celeritas celeritas-project.github.io Celeritas is a new Monte Carlo transport code designed to accelerate scientific discovery | 105 | Codex, OpenCode | 1 | 2,452 tok |
| wybert/earth-agent-chrome-ext Earth Agent is a Cursor-like AI agent for Google Earth Engine. It can be used right in you | 104 | Claude Code, Gemini CLI | 2 | 965 tok |
| olibartfast/neuriplo-infer C++ app for computer vision inference, supporting multiple tasks and backends. | 103 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 2,281 tok |
| potatobeanradio/circuitRF Lightweight cross-platform RF circuit simulator — DC, S-parameters, harmonic balance, load | 103 | Claude Code | 1 | 9,876 tok |
| fl-sean03/OpenSDL seanflorez.com A modular Python foundation for reproducible computational and autonomous laboratories. Al | 102 | Claude Code, Codex, OpenCode | 13 | 921 tok |
| cmu-phil/py-tetrad Makes algorithms/code in Tetrad available in Python via JPype | 99 | Claude Code | 2 | 1,020 tok |
| xd-liu/AutoResearch-Idea | 99 | Claude Code | 11 | 2,294 tok |
| aws-samples/aws-hpc-recipes Contains example recipes that demonstrate how to build HPC systems using AWS services and | 97 | Claude Code, Codex, OpenCode | 2 | 1,033 tok |
| eunomia-bpf/ActPlane eunomia.dev eBPF Information Flow Enforcement for AI Agent safety, security and effectiveness | 97 | Claude Code, Codex, OpenCode | 6 | 2,205 tok |
| gokeshenzhen/TraceWeave A universal MCP Server for test platform logs, waveforms (FSDB/VCD), and root cause analys | 97 | Claude Code, Codex, OpenCode | 2 | 8,348 tok |
| plclub/hs-to-rocq hs-to-coq.readthedocs.io Convert Haskell source code to Coq source code. | 96 | Claude Code | 4 | 6,009 tok |
| joelreymont/pz Minimal pi coding-agent re-implementation in Zig | 95 | Claude Code, Codex, OpenCode | 6 | 1,186 tok |
| CliMA/Thermodynamics.jl clima.github.io Fast, differentiable moist thermodynamics for Earth system models. | 93 | Codex, OpenCode | 1 | 699 tok |
| statsclaw/statsclaw statsclaw.ai A workflow framework for statistical package development | 92 | Claude Code | 2 | 25 tok |
| cyanheads/clinicaltrialsgov-mcp-server npmjs.com Search ClinicalTrials.gov trials, retrieve study details and results, and match patients t | 91 | Claude Code, Codex, OpenCode | 2 | 11,808 tok |
| iLearn-Lab/ACL25-AdaReTaKe Official implementation of paper AdaReTaKe: Adaptive Redundancy Reduction to Perceive Long | 91 | Codex, OpenCode | 1 | 2,221 tok |
| IlyaGusev/academia_mcp smithery.ai Academia MCP server: Tools for automatic scientific research | 91 | Claude Code | 1 | 2,701 tok |
| Dicklesworthstone/brenner_bot brennerbot.org Harness the scientific methods of Sydney Brenner using AI Agents | 90 | Codex, OpenCode | 1 | 6,951 tok |
| tensorcircuit/tensorcircuit-ng tensorcircuit-ng.readthedocs.io Next-gen AI-native tensor-network-based quantum software framework | 89 | Claude Code, Codex, OpenCode | 12 | 1,294 tok |
| Ayueh0102/Ronnier-skill Comprehensive Chinese study notes on color science/colorimetry, packaged as a Claude Code | 88 | Codex, OpenCode | 1 | 2,042 tok |
| 0xSanei/darwinia colab.research.google.com The Self-Evolving Agent Ecosystem — Trading agents that evolve through Darwinian selection | 87 | Claude Code, Codex, OpenCode | 3 | 1,631 tok |
| linzhe001/Harness-Research | 86 | Claude Code, Codex | 26 | — |
| Routhleck/myNotes routhleck.github.io Software Engineering course notes from Beijing Jiaotong University | 86 | Codex, OpenCode | 1 | 681 tok |
| jmrplens/TFG-TFM_EPS jmrp.io Plantilla LaTeX para la elaboración de TFG y TFM en la Escuela Politécnica Superior de la | 84 | Claude Code, Codex, GitHub Copilot, OpenCode | 3 | 11,314 tok |
| tririver/arc Agent Research Copilot (ARC) is a set of skills and tools (CLI) for theoretical physics li | 83 | Codex, OpenCode | 1 | 3,116 tok |
| THU-Team-Eureka/EurekAgent EurekAgent: an autonomous research system for metric-driven tasks, built with Claude Code. | 82 | Claude Code | 4 | — |
| Lambenthan/empiricalwiki AI knowledge base for empirical research in economics and management — a complete pipeline | 82 | Claude Code, Codex, OpenCode | 31 | 4,874 tok |
| zxyasfas/paper_format_agent DOCX formatter for academic papers with a content-fingerprint guard: proves your text is n | 80 | Codex, OpenCode | 1 | 210 tok |
| gpt-cmdr/ras-commander clbengineering.com The RAS-Commander library provides a python API and agentic features for automating HEC-RA | 79 | Claude Code, Codex, OpenCode | 71 | 2,986 tok |
| mituan-ai/PaperBanana-CN Scientific figure workbench with independent VLM/image connections, Chinese UI, and unifie | 78 | Claude Code, GitHub Copilot | 4 | 445 tok |
| jaylfc/taosmd Local-first AI memory — runs offline on any machine with 8 GB+ RAM (SBC, mini PC, laptop, | 77 | Claude Code, Codex, OpenCode | 3 | 3,177 tok |
| AMD-AGI/Apex Agents, and RL environment, for optimizing GPU kernels on AMD ROCm using LLM agents. Bench | 76 | Claude Code, Codex, OpenCode | 2 | 19,966 tok |
| dermatologist/pyomop nuchange.ca Python package for managing OHDSI clinical data models. Includes support for LLM based pla | 66 | Claude Code, Codex, OpenCode | 2 | 551 tok |
| ALBDNDJ/hpcguard A user-space safety net that helps researchers prevent AI agents from overloading shared H | 65 | Codex, OpenCode | 1 | 509 tok |
| yorkeccak/scientific-skills Natural language scientific literature search skills with semantic search over PubMed, arX | 61 | Claude Code | 1 | 78 tok |