rna-seq-analysis

rna-seq-analysis is a skill for Claude Code, Codex from awslabs/hcls-agent-skills. It costs 103 tokens per session (1,332 once invoked), scanned A, original, MIT-0.

A workflow for analyzing bulk RNA sequencing data, which measures gene activity across a group of cells or a tissue sample. It covers read alignment or quantification and statistical comparison of gene expression.

In plain words
What is it for?
It is for aligning reads with STAR, quantifying transcripts with Salmon or featureCounts, importing transcript estimates with tximport, and finding differential expression with DESeq2.
Why use it?
It organizes the steps needed to identify genes whose activity differs between experimental conditions.

Skill for Claude CodeCodex ✓ vendor

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

Good fit It is for aligning reads with STAR, quantifying transcripts with Salmon or featureCounts, importing transcript estimates with tximport, and finding differential expression with DESeq2.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/awslabs/hcls-agent-skills/rna-seq-analysis
About the project

awslabs/hcls-agent-skills is a collection of reusable instructions that help AI agents handle healthcare and life sciences work, including genomics, medical imaging, claims, and drug discovery. It is intended for agents running on Agent Skills-compatible platforms, and the catalogue entries are its individual domain skills.

awslabs/hcls-agent-skills · 33 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add awslabs/hcls-agent-skills --skill rna-seq-analysis
Clone the repo
git clone --depth 1 https://github.com/awslabs/hcls-agent-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for rna-seq-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/awslabs/hcls-agent-skills/rna-seq-analysis/github.svg)](https://agentmods.dev/skills/awslabs/hcls-agent-skills/rna-seq-analysis)
Your own site
<a href="https://agentmods.dev/skills/awslabs/hcls-agent-skills/rna-seq-analysis"><img src="https://agentmods.dev/badge/skills/awslabs/hcls-agent-skills/rna-seq-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for rna-seq-analysis

Your own site · 80×15
<a href="https://agentmods.dev/skills/awslabs/hcls-agent-skills/rna-seq-analysis"><img src="https://agentmods.dev/badge/skills/awslabs/hcls-agent-skills/rna-seq-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 103 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,332 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00103 $0.01332
Opus 5 $0.00051 $0.00666
Sonnet 5 $0.00021 $0.00266
Haiku 4.5 $0.00010 $0.00133

Measured 12d ago against content hash 0477a8ca74d5, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

rna-seq-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/deseq2_contrast.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/rna-seq-analysis/SKILL.md · 110 lines

The source is not reproduced here

Licensed MIT-0

The repository is licensed MIT-0, which this catalogue does not treat as permission to reproduce the file. Read it at the source.

Read it on GitHub

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 110 lines · 103 tokens per session scan A 0477a8ca74d5

Subscribe to this mod's changes

rna-seq-analysis is a skill published in the GitHub repository awslabs/hcls-agent-skills (33 stars, last pushed 11d ago), licensed MIT-0. It adds 103 tokens to every session and 1,332 once invoked, about $0.0005 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

Other skills, from other repositories

bulk-transcriptomics

Bulk RNA-seq and microarray differential expression analysis including method selection, batch correction, and complex experimental designs.

inflexa-ai/inflexa · 26 tokens

sc-de

Load when finding marker genes per cluster or comparing condition expression in single-cell RNA-seq. Skip when the data is bulk (use bulkrna-de); spatial (use spatial-de); cluster-only markers without conditions (use sc-markers).

TianGzlab/OmicsClaw · 51 tokens

bulkrna-de

Load when comparing gene expression between two conditions in bulk RNA-seq count data. Skip when the data is single-cell (use sc-de); spatial (use spatial-de); you need exon-level alternative splicing (use bulkrna-splicing).

TianGzlab/OmicsClaw · 54 tokens

spatial-condition-comparison

Experimental condition comparison using pseudobulk differential expression with proper multi-sample statistics.

ShangBioLab/SpatialClaw · 22 tokens

scanpy

Standard single-cell RNA-seq analysis pipeline. Use for QC, normalization, dimensionality reduction (PCA/UMAP/t-SNE), clustering, differential expression, and visualization. Best for exploratory scRNA-seq analysis with established workflows. For deep learning models use scvi-tools; for data format questions use…

synthetic-sciences/openscience · 68 tokens

bias-detection

Assess systematic biases in the evidence body — publication bias, reporting bias, and selective outcome reporting. Budget: 40 studies, 40 effect sizes, 40 web searches.

yogsoth-ai/de-anthropocentric-research-engine · 39 tokens