thesecondfox/skill

3Stars on the repository
200Mods indexed here, across every type
5mo agoLast push, which is what freshness is scored on
MITLicence, which decides whether bodies are shown

thesecondfox/skill

Skill Claude CodeCodex

Draw and export phylogenetic trees using Biopython Bio.Phylo with matplotlib. Use when creating publication-quality tree figures, customizing colors and labels, or exporting to image formats.

not rated 3 5mo ago A 46 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Validate PCR primers for specificity, dimers, hairpins, and secondary structures using primer3-py thermodynamic calculations. Check self-complementarity, heterodimer formation, and 3' stability. Use when validating primer specificity and properties.

not rated 3 5mo ago A 57 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Design qPCR primers and TaqMan/molecular beacon probes using primer3-py. Configure probe Tm, primer-probe spacing, and hydrolysis probe constraints for real-time PCR assays. Use when designing qPCR primers and probes.

not rated 3 5mo ago A 59 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Generates standardized quality control reports by aggregating metrics from FastQC, alignment, and other tools using MultiQC. Use when summarizing QC metrics across samples, creating shareable quality reports, or building automated QC pipelines.

not rated 3 5mo ago A 55 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Exports publication-ready figures in various formats with proper resolution, sizing, and typography. Use when preparing figures for journal submission, creating vector graphics for presentations, or ensuring consistent figure styling across analyses.

not rated 3 5mo ago A 45 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Creates reproducible Jupyter notebooks for bioinformatics analysis with parameterization using papermill. Use when generating automated analysis reports, running notebook-based pipelines, or creating shareable computational notebooks.

not rated 3 5mo ago A 45 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Build reproducible scientific documents, presentations, and websites with Quarto supporting R, Python, Julia, and Observable JS. Use when creating reproducible reports with Quarto.

not rated 3 5mo ago A 42 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Create reproducible bioinformatics analysis reports with R Markdown including code, results, and visualizations in HTML, PDF, or Word format. Use when generating analysis reports with RMarkdown.

not rated 3 5mo ago A 44 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Select restriction enzymes by criteria using Biopython Bio.Restriction. Find enzymes that cut once, don't cut, produce specific overhangs, are commercially available, or have compatible ends for cloning. Use when selecting restriction enzymes for cloning or analysis.

not rated 3 5mo ago A 57 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Analyze restriction digest fragments using Biopython Bio.Restriction. Predict fragment sizes, get fragment sequences, simulate gel electrophoresis patterns, and perform double digests. Use when analyzing restriction digest fragment patterns.

not rated 3 5mo ago A 49 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Create restriction maps showing enzyme cut positions on DNA sequences using Biopython Bio.Restriction. Visualize cut sites, calculate distances between sites, and generate text or graphical maps. Use when creating or analyzing restriction maps.

not rated 3 5mo ago A 50 tokens original MIT

bio-restriction-sites

108

thesecondfox/skill

Skill Claude CodeCodex

Find restriction enzyme cut sites in DNA sequences using Biopython Bio.Restriction. Search with single enzymes, batches of enzymes, or commercially available enzyme sets. Returns cut positions for linear or circular DNA. Use when finding restriction enzyme cut sites in sequences.

not rated 3 5mo ago A 56 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Searches for non-coding RNA homologs and classifies RNA families using Infernal covariance model searches against the Rfam database. Identifies structured RNAs by sequence and secondary structure conservation. Use when querying sequences against Rfam, building custom covariance models for novel RNA families, or…

not rated 3 5mo ago A 75 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Predicts RNA secondary structures using minimum free energy folding and partition function analysis with ViennaRNA (RNAfold, RNAalifold, RNAcofold). Computes base-pair probabilities, centroid structures, and consensus structures from alignments. Use when predicting RNA folding, evaluating structural stability, or…

not rated 3 5mo ago A 74 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Analyzes experimental RNA structure probing data from SHAPE-MaP and DMS-MaPseq experiments using ShapeMapper2. Converts mutation rates to per-nucleotide reactivity profiles that constrain structure prediction. Use when processing SHAPE-MaP or DMS-MaPseq sequencing data to obtain experimental RNA structure information.

not rated 3 5mo ago A 75 tokens original MIT

bio-codon-usage

112

thesecondfox/skill

Skill Claude CodeCodex

Analyze codon usage, calculate CAI (Codon Adaptation Index), and examine synonymous codon bias using Biopython. Use when analyzing coding sequences for expression optimization or evolutionary analysis.

not rated 3 5mo ago A 44 tokens original MIT

bio-motif-search

113

thesecondfox/skill

Skill Claude CodeCodex

Find patterns, motifs, and subsequences in biological sequences using Biopython. Use when searching for transcription factor binding sites, regulatory elements, or any sequence pattern. For restriction enzyme analysis, use the restriction-analysis skill.

not rated 3 5mo ago A 49 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Generate reverse complements and complements of DNA/RNA sequences using Biopython. Use when working with opposite strands, primer design, or converting between template and coding strands.

not rated 3 5mo ago A 39 tokens original MIT

bio-seq-objects

115

thesecondfox/skill

Skill Claude CodeCodex

Create and manipulate Seq, MutableSeq, and SeqRecord objects using Biopython. Use when creating sequences from strings, modifying sequence data in-place, or building annotated sequence records.

not rated 3 5mo ago A 42 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Calculate sequence properties like GC content, molecular weight, isoelectric point, and GC skew using Biopython. Use when analyzing sequence composition, computing physical properties, or comparing sequences.

not rated 3 5mo ago A 42 tokens original MIT

bio-sequence-slicing

117

thesecondfox/skill

Skill Claude CodeCodex

Slice, extract, and concatenate biological sequences using Biopython. Use when extracting subsequences, joining sequences, or manipulating sequence regions by position.

not rated 3 5mo ago A 35 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Transcribe DNA to RNA and translate to protein using Biopython. Use when converting between DNA, RNA, and protein sequences, finding ORFs, or using alternative codon tables.

not rated 3 5mo ago A 43 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images. Use when visualizing spatial expression patterns.

not rated 3 5mo ago A 52 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

Build tissue and condition-specific metabolic models using GIMME, iMAT, and INIT algorithms with expression data constraints. Create models that reflect cell-type specific metabolism. Use when building tissue-specific metabolic models or integrating transcriptomics with FBA.

not rated 3 5mo ago A 57 tokens original MIT

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