sc-qc

sc-qc is a skill for Claude Code, Codex from TianGzlab/OmicsClaw. It costs 60 tokens per session (1,004 once invoked), scanned A, original, Apache-2.0.

A single-cell data quality report for an AnnData file, measuring genes detected, total counts, and mitochondrial and ribosomal read percentages for each cell.

In plain words
What is it for?
Reviewing cell-level quality metrics and exporting tables, charts, and a processed AnnData file for later analysis.
Why use it?
It shows which cells may be low quality before you decide whether to remove them. It reports these measurements but does not filter cells.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Reviewing cell-level quality metrics and exporting tables, charts, and a processed AnnData file for later analysis.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/tiangzlab/omicsclaw/sc-qc
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add TianGzlab/OmicsClaw --skill sc-qc
Clone the repo
git clone --depth 1 https://github.com/TianGzlab/OmicsClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for sc-qc

README.md
[![agentmods](https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-qc/github.svg)](https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-qc)
Your own site
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-qc"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-qc/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for sc-qc

Your own site · 80×15
<a href="https://agentmods.dev/skills/tiangzlab/omicsclaw/sc-qc"><img src="https://agentmods.dev/badge/skills/tiangzlab/omicsclaw/sc-qc.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 60 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,004 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Rogue Agent · line 3
    Skill modifies its own code, configuration, or behavior at runtime. Self-modification enables an agent to escalate privileges, disable safety constraints, or install persistent backdoors.
    Fix: Prevent the skill from modifying its own code, SKILL.md, or configuration files. Treat skill files as read-only at runtime.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00060 $0.01004
Opus 5 $0.00030 $0.00502
Sonnet 5 $0.00012 $0.00201
Haiku 4.5 $0.00006 $0.00100

Measured 5d ago against content hash 6863f1f208f0, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

sc-qc scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 5d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (sc_qc.py, tests/test_sc_qc.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/singlecell/scrna/sc-qc/SKILL.md · 104 lines

How it starts

The opening of the file, as written. The whole thing — 104 lines — stays where its author put it; the contents beside it link to each section on GitHub.

sc-qc

When to use

The user has a single-cell AnnData (post-counting / post-standardisation) and wants to review cell quality — counts, detected genes, mitochondrial percentage, ribosomal percentage — before any filtering. This skill reports, it does not remove cells. Use sc-filter to actually drop cells based on these metrics.

Inputs & Outputs

Inputs

  • Modalities: scrna
  • File types: .h5ad

Outputs

  • tables/barcode_rank_curve.csv
  • tables/cell_metadata.csv
  • tables/gene_expression.csv
  • tables/highest_expr_genes.csv
  • tables/qc_metric_correlations.csv
  • tables/qc_metrics_per_cell.csv
  • tables/qc_metrics_summary.csv
  • tables/qc_run_summary.csv
  • figures/barcode_rank.png
  • figures/highest_expr_genes.png
  • figures/qc_correlation_heatmap.png
  • figures/qc_histograms.png
  • figures/qc_scatter.png
  • figures/qc_violin.png
  • figures/r_qc_violin.png
  • analysis_summary.txt
  • processed.h5ad
  • report.md
  • result.json
  • Processed AnnData (saves_h5ad)

Flow

  1. Load AnnData via the shared single-cell loader.
  2. Detect mitochondrial / ribosomal gene patterns from species hint (or var_names heuristic).
  3. Compute per-cell QC metrics with scanpy.pp.calculate_qc_metrics.
  4. Emit summary stats + per-cell metrics tables.
  5. Render violin + scatter figures and tables/highest_expr_genes.csv.
  6. Emit report.md + result.json (no cell filtering performed).

Gotchas

  • No filtering happens here. Despite the name, sc-qc does not remove cells or genes — it computes metrics and produces figures. Run sc-filter next with thresholds chosen from the QC violins. The result.json summary carries n_cells / n_genes as observed, not as filtered.
  • Input file missing → hard fail. sc_qc.py:635 raises FileNotFoundError when --input does not resolve. Pre-flight your path before the skill, especially in batch pipelines.
  • expression_source records which matrix the run used. result.json["summary"]["expression_source"] reads layers.counts, adata.raw, or adata.X depending on what the loader picked; QC fractions (mt%, ribo%) are only meaningful on a count-like source. Verify after every run, especially if the input came from outside sc-standardize-input.

Read the full file on GitHub · 104 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 5d ago First seen · 104 lines · 60 tokens per session scan A 6863f1f208f0

Subscribe to this mod's changes

sc-qc is a skill published in the GitHub repository TianGzlab/OmicsClaw (160 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 60 tokens to every session and 1,004 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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